loading...| Preferred Name | Diazepam | |
| Synonyms |
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|
| Definitions |
A benzodiazepine derivative with anti-anxiety, sedative, hypnotic and anticonvulsant properties. Diazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic system and the hypothalamus. This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C28982 |
|
| ALT_DEFINITION |
A drug used to treat mild to moderate anxiety and tension and to relax muscles. It is a type of benzodiazepine. |
|
| CAS_Registry |
439-14-5 |
|
| CHEBI_ID |
CHEBI:49575 |
|
| Chemical_Formula |
C16H13ClN2O |
|
| code |
C28982 |
|
| Contributing_Source |
CPTAC CTRP FDA |
|
| definition |
A benzodiazepine derivative with anti-anxiety, sedative, hypnotic and anticonvulsant properties. Diazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic system and the hypothalamus. This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability. |
|
| Display_Name |
Diazepam |
|
| FDA_UNII_Code |
Q3JTX2Q7TU |
|
| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Diazepam |
|
| Legacy Concept Name |
Diazepam |
|
| NSC Number |
169897 46083 77518 |
|
| Preferred_Name |
Diazepam |
|
| prefixIRI |
NCIT:C28982 |
|
| prefLabel |
Diazepam |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0012010 |
|
| subClassOf |