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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Rheumatoid Arthritis | |
| Synonyms |
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| Definitions |
A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C2884 |
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| ALT_DEFINITION |
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. A chronic, inflammatory condition manifesting primarily as a symmetric, erosive, polyarthritis that spares the axial skeleton and is typically associated with rheumatoid factor and anti-citrullinated protein antibodies. An autoimmune disease that causes pain, swelling, and stiffness in the joints, and may cause severe joint damage, loss of function, and disability. The disease may last from months to a lifetime, and symptoms may improve and worsen over time.
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| code |
C2884
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| Contributing_Source |
CPTAC FDA GDC NICHD
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| database_cross_reference |
IMDRF:E160201
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| definition |
A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.
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| FDA_Table |
Patient Code (Appendix B)
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C62596 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C54450 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C158035 |
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| Is_Value_For_GDC_Property | ||
| label |
Rheumatoid Arthritis
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| Legacy Concept Name |
Rheumatoid_Arthritis
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| Maps_To |
Rheumatoid Arthritis
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| Preferred_Name |
Rheumatoid Arthritis
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| prefixIRI |
NCIT:C2884
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| prefLabel |
Rheumatoid Arthritis
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| Semantic_Type |
Disease or Syndrome
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| UMLS_CUI |
C0003873
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| subClassOf |
http://purl.obolibrary.org/obo/NCIT_C27204 |
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