loading...| Preferred Name | Rickets | |
| Synonyms |
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| Definitions |
Bone softening and weakening usually caused by deficiency or impaired metabolism of vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets. It predominantly affects children who suffer from severe malnutrition. It manifests with bone pain, fractures, muscle weakness, and skeletal deformities. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C26878 |
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| ALT_DEFINITION |
A disorder of defective chondrocyte differentiation and mineralization of the epiphyseal plate due to deficiency of calcium, phosphate, or vitamin D. Rickets can manifest clinically with features such as craniotabes, costrochondral junction enlargement, widening of the wrists and ankles, lower extremity bowing, and failure to thrive. This condition is diagnosed radiographically, and is characterized by growth plate widening as well as metaphyseal cupping and fraying. |
|
| code |
C26878 |
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| Contributing_Source |
MedDRA NICHD |
|
| definition |
Bone softening and weakening usually caused by deficiency or impaired metabolism of vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets. It predominantly affects children who suffer from severe malnutrition. It manifests with bone pain, fractures, muscle weakness, and skeletal deformities. |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C118467 |
|
| label |
Rickets |
|
| Legacy Concept Name |
Rickets |
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| Maps_To |
Rickets |
|
| Preferred_Name |
Rickets |
|
| prefixIRI |
NCIT:C26878 |
|
| prefLabel |
Rickets |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C1848337 |
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| subClassOf |