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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Fibronectin | |
| Synonyms |
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| Definitions |
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C16581 |
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| code |
C16581
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| Contributing_Source |
CTRP
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| definition |
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis.
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| DesignNote |
Fibronectin can be cleaved to form Ugl-Y1, Ugl-Y2, Ugl-Y3 and anastellin. (UniProt) Anastellin is a 76 amino acid fragment from carboxy-terminal portion of the first fibronectin type-III domain with potential antiangiogenic activity. Anastellin binds fibronectin and induces fibril formation; the resulting fibronectin polymer, superfibronectin, exhibits enhanced adhesive properties and may also inhibit angiogenesis. (UniProt)
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| Display_Name |
Fibronectin
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Fibronectin
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| Legacy Concept Name |
Fibronectin
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| NCI_META_CUI |
CL1379609
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| OMIM_Number |
135600
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| Preferred_Name |
Fibronectin
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| prefixIRI |
NCIT:C16581
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| prefLabel |
Fibronectin
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| Semantic_Type |
Amino Acid, Peptide, or Protein
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| Swiss_Prot |
P02751
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| subClassOf |
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