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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Ritonavir | |
| Synonyms |
|
|
| Definitions |
A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1609 |
|
| ALT_DEFINITION |
A drug used to treat infection with HIV (the virus that causes AIDS). It is also being studied in the treatment of some types of cancer. Ritonavir blocks the ability of HIV to make copies of itself and may block the growth of cancer cells. It is a type of anti-HIV agent and a type of protease inhibitor.
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| CAS_Registry |
155213-67-5
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|
| CHEBI_ID |
CHEBI:45409
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| Chemical_Formula |
C37H48N6O5S2
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|
| code |
C1609
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|
| Contributing_Source |
CTRP FDA
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|
| definition |
A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450.
|
|
| Display_Name |
Ritonavir
|
|
| FDA_UNII_Code |
O3J8G9O825
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|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Ritonavir
|
|
| Legacy Concept Name |
Ritonavir
|
|
| NCI_Drug_Dictionary_ID |
42665
|
|
| NSC Number |
693184
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|
| PDQ_Closed_Trial_Search_ID |
42665
|
|
| PDQ_Open_Trial_Search_ID |
42665
|
|
| Preferred_Name |
Ritonavir
|
|
| prefixIRI |
NCIT:C1609
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|
| prefLabel |
Ritonavir
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0292818
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|
| subClassOf |
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