Preferred Name

Resveratrol
Synonyms
Definitions

A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. (NCI05)

ID

http://purl.obolibrary.org/obo/NCIT_C1215

ALT_DEFINITION

A substance found in the skins of grapes and in certain other plants, fruits, and seeds. It is made by various plants to help defend against invading fungi, stress, injury, infection, and too much sunlight. It is being studied in the prevention of cancer and heart disease. It is a type of antioxidant and a type of polyphenol.

CAS_Registry

501-36-0

CHEBI_ID

CHEBI:27881

CHEBI:45713

Chemical_Formula

C14H12O3

code

C1215

Contributing_Source

CTRP

FDA

definition

A phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. (NCI05)

Display_Name

Resveratrol

FDA_UNII_Code

Q369O8926L

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C173383

http://purl.obolibrary.org/obo/NCIT_C173381

http://purl.obolibrary.org/obo/NCIT_C177537

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

http://purl.obolibrary.org/obo/NCIT_C128784

http://purl.obolibrary.org/obo/NCIT_C157711

http://purl.obolibrary.org/obo/NCIT_C157712

http://purl.obolibrary.org/obo/NCIT_C142799

Is_Value_For_GDC_Property

http://purl.obolibrary.org/obo/NCIT_C1909

label

Resveratrol

Legacy Concept Name

Resveratrol

Maps_To

Resveratrol

NCI_Drug_Dictionary_ID

405819

NSC Number

327430

PDQ_Closed_Trial_Search_ID

405819

PDQ_Open_Trial_Search_ID

405819

Preferred_Name

Resveratrol

prefixIRI

NCIT:C1215

prefLabel

Resveratrol

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0073096

subClassOf

http://purl.obolibrary.org/obo/NCIT_C54630

http://purl.obolibrary.org/obo/NCIT_C275

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Mapping To Ontology Source
http://purl.bioontology.org/ontology/PDQ/CDR0000405819 PDQ LOOM
http://purl.obolibrary.org/obo/ARO_3007614 ARO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 DRON LOOM
http://purl.obolibrary.org/obo/XCO_0000856 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 CHEBI LOOM
https://go.drugbank.com/drugs/DB02709 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/96383001 SNOMEDCT LOOM
http://www.pepathway.org/peo/1.2#Resveratrol PE-O LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0073096 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4026034 VANDF LOOM
http://purl.jp/bio/4/id/200906085193911422 IOBC LOOM
http://purl.obolibrary.org/obo/dinto_DB02709 DINTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1215 NCIT LOOM
http://purl.bioontology.org/ontology/SNMI/C-A6595 SNMI LOOM
http://purl.bioontology.org/ontology/RXNORM/1000492 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D000077185 MESH LOOM
http://stirdf.jst.go.jp/id/200907035397714703 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000176093 NDFRT LOOM
http://doe-generated-ontology.com/OntoAD#C0073096 ONTOAD LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000405819 PDQ LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C059514 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/013210 NDDF LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 FOODON LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 FOBI LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_27881 EFO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#14749 OCHV LOOM