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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Severe Preeclampsia | |
| Synonyms |
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| Definitions |
Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C112843 |
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| ALT_DEFINITION |
Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances. Preeclampsia with Severe Features is defined by three criteria: First, the gestational age of he pregnancy must be equal to or greater than 20 weeks; Second, a diagnosis of new onset maternal hypertension (systolic blood pressure equal or greater than 140mmHg and /or diastolic blood pressure equal to or greater than 90mmHg) that is sustained on two measurements over a minimum of one hour; Third, at least one of the criteria for severe disease.
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| code |
C112843
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| Contributing_Source |
GAIA NICHD
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| definition |
Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C126860 |
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| label |
Severe Preeclampsia
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| Preferred_Name |
Severe Preeclampsia
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| prefixIRI |
NCIT:C112843
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| prefLabel |
Severe Preeclampsia
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| Semantic_Type |
Disease or Syndrome
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| UMLS_CUI |
C4228546
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| subClassOf |
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