Preferred Name

Antithrombin-III
Synonyms
Definitions

Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation.

ID

http://purl.obolibrary.org/obo/NCIT_C104683

code

C104683

Contributing_Source

CTRP

definition

Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation.

DesignNote

Antithrombin-III can inhibit thrombin, matriptase-3/TMPRSS7, and coagulation factors IXa, Xa and Xia. (UniProt)

Display_Name

Antithrombin-III

in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C142800

http://purl.obolibrary.org/obo/NCIT_C142799

label

Antithrombin-III

NCI_META_CUI

CL360008

OMIM_Number

107300

Preferred_Name

Antithrombin-III

prefixIRI

NCIT:C104683

prefLabel

Antithrombin-III

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P01008

subClassOf

http://purl.obolibrary.org/obo/NCIT_C17122

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Mapping To Ontology Source
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antithrombin-III SEPON LOOM
http://purl.obolibrary.org/obo/DRON_00012870 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00012870 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00012870 DDSS LOOM
http://purl.obolibrary.org/obo/dinto_1192 DINTO LOOM
http://purl.jp/bio/4/id/200906075874884142 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.822.750.060.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1009 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/B01AB02 ATC LOOM
http://purl.bioontology.org/ontology/RCD/X80WP RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021438 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.113.025 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.377.715.085.125 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0003438 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4023295 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.861.060.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/PR_000003252 PR LOOM
http://purl.obolibrary.org/obo/PR_000003252 PDRO LOOM
http://purl.obolibrary.org/obo/PR_000003252 OBI LOOM
http://purl.obolibrary.org/obo/PR_000003252 ONE LOOM
http://purl.obolibrary.org/obo/PR_000003252 EGO LOOM
http://purl.obolibrary.org/obo/PR_000003252 OBI_IEE LOOM
http://purl.obolibrary.org/obo/PR_000003252 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.872.060.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1327 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/F-D8320 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.124.790.106.125 RH-MESH LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02389 MIO LOOM
http://purl.bioontology.org/ontology/CSP/0437-1452 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.645.750.060.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000021300 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000990 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104683 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/34086003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MEDDRA/10050640 MEDDRA LOOM
http://purl.bioontology.org/ontology/MESH/D000990 MESH LOOM
http://purl.uniprot.org/uniprot/P01008 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0002384 OMIT LOOM