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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Beta-Carotene | |
| Synonyms |
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| Definitions |
A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C1016 |
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| Accepted_Therapeutic_Use_For |
Dietary supplement; prevention of photosensitivity reactions in patients with erythropoietic protoporphyria; polymorphous light eruption; chemoprevention for cardiovascular disease and cancer
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| ALT_DEFINITION |
Carotenoid consisting of a cyclic structure on each end with additional double bonds at the number 5 and 5' carbon atoms of the cyclic structures. A substance found in yellow and orange fruits and vegetables and in dark green, leafy vegetables. The body can make vitamin A from beta carotene. Beta carotene is being studied in the prevention of some types of cancer. It is a type of antioxidant.
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| CAS_Registry |
7235-40-7
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| CHEBI_ID |
CHEBI:17579
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| Chemical_Formula |
C40H56
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| code |
C1016
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| Contributing_Source |
CRCH FDA
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|
| definition |
A naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. This agent also induces cell differentiation and apoptosis of some tumor cell types, particularly in early stages of tumorigenesis, and enhances immune system activity by stimulating the release of natural killer cells, lymphocytes, and monocytes. (NCI04)
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| FDA_UNII_Code |
01YAE03M7J
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| INFOODS |
CARTB
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| Is_Value_For_GDC_Property | ||
| label |
Beta-Carotene
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|
| Legacy Concept Name |
Beta_Carotene
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| Maps_To |
Beta-Carotene
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| NCI_Drug_Dictionary_ID |
40992
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| NSC Number |
62794
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| PDQ_Closed_Trial_Search_ID |
40992
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| PDQ_Open_Trial_Search_ID |
40992
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| Preferred_Name |
Beta-Carotene
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|
| prefixIRI |
NCIT:C1016
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|
| prefLabel |
Beta-Carotene
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| Semantic_Type |
Pharmacologic Substance Vitamin
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| UMLS_CUI |
C0053396
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|
| Unit |
mcg
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| USDA_ID |
321
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| subClassOf |
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