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Biological and Environmental Research Ontology
| Preferred Name | dextromethorphan | |
| Synonyms |
D-methorphan 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan (+)-dextromethorphan Balminil DM (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan d-Methorphan destrometerfano dextromethorphan dextromethorphane (+)-3-methoxy-N-methylmorphinan dextromethorphanum dextrometorfano Dextromorphan dextromethorfan Albutussin Antussan BA 2666 BA-2666 Benylin DM Calmylin DXM Delsym Medicon Romilar Tusilan (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene |
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| Definitions |
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4470 |
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| alternative term |
D-methorphan 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan (+)-dextromethorphan Balminil DM (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan d-Methorphan destrometerfano dextromethorphan dextromethorphane (+)-3-methoxy-N-methylmorphinan dextromethorphanum dextrometorfano Dextromorphan dextromethorfan Albutussin Antussan BA 2666 BA-2666 Benylin DM Calmylin DXM Delsym Medicon Romilar Tusilan (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
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| bearer of |
http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_50910 http://purl.obolibrary.org/obo/CHEBI_78298 http://purl.obolibrary.org/obo/CHEBI_60643 http://purl.obolibrary.org/obo/CHEBI_50266 |
|
| charge |
0
|
|
| database_cross_reference |
Drug_Central:842 KEGG:D03742 PMID:17573115 PMID:8158182 PMID:12711372 PMID:15505150 PMID:7976530 DrugBank:DB00514 PMID:9705419 LINCS:LSM-2726 KEGG:C06947 CAS:125-71-3 PMID:18160193 PMID:18198471 PMID:2660263 Reaxys:88549 PMID:31094746 Wikipedia:Dextromethorphan PMID:24269965 PMID:17461892 PMID:10869398 PMID:17157116 HMDB:HMDB0001920
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|
| definition |
A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
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|
| formula |
C18H25NO
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| has_alternative_id |
CHEBI:92579
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| has_exact_synonym |
(4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
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| has_functional_parent | ||
| has_obo_namespace |
chebi_ontology
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| has_related_synonym |
D-methorphan 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan (+)-dextromethorphan Balminil DM (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan d-Methorphan destrometerfano dextromethorphan dextromethorphane (+)-3-methoxy-N-methylmorphinan dextromethorphanum dextrometorfano Dextromorphan dextromethorfan Albutussin Antussan BA 2666 BA-2666 Benylin DM Calmylin DXM Delsym Medicon Romilar Tusilan
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|
| id |
CHEBI:4470
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| in_subset | ||
| inchi |
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
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|
| inchikey |
MKXZASYAUGDDCJ-NJAFHUGGSA-N
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| is_enantiomer_of | ||
| label |
dextromethorphan
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|
| mass |
271.404
|
|
| monoisotopicmass |
271.19361
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|
| notation |
CHEBI:4470
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|
| prefLabel |
dextromethorphan
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| RO_0000087 |
http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_50910 http://purl.obolibrary.org/obo/CHEBI_78298 http://purl.obolibrary.org/obo/CHEBI_60643 http://purl.obolibrary.org/obo/CHEBI_50266 |
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| smiles |
C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H]
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| subClassOf |
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