loading...| Preferred Name | apoptotic process | |
| Synonyms |
apoptosis signaling type I programmed cell death apoptosis activation of apoptosis apoptotic program apoptosis activator activity induction of apoptosis by p53 signaling (initiator) caspase activity commitment to apoptosis induction of apoptosis caspase-dependent programmed cell death cell suicide cellular suicide apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
|
| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
|
| database_cross_reference |
Wikipedia:Apoptosis |
|
| has exact synonym |
apoptotic cell death programmed cell death by apoptosis apoptotic programmed cell death |
|
| has_alternative_id |
GO:0008632 GO:0006917 |
|
| has_broad_synonym |
cell suicide cellular suicide |
|
| has_narrow_synonym |
apoptosis signaling type I programmed cell death apoptosis activation of apoptosis apoptotic program |
|
| has_obo_namespace |
biological_process |
|
| has_related_synonym |
apoptosis activator activity induction of apoptosis by p53 signaling (initiator) caspase activity commitment to apoptosis induction of apoptosis caspase-dependent programmed cell death |
|
| id |
GO:0006915 |
|
| imported from | ||
| label |
apoptotic process |
|
| notation |
GO:0006915 |
|
| prefixIRI |
GO:0006915 |
|
| prefLabel |
apoptotic process |
|
| RO_0002161 | ||
| textual definition |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
|
| subClassOf |
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