loading...| Preferred Name |
thapsigargin |
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| Synonyms |
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| Definitions |
An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_9516 |
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| definition |
An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations. |
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| label |
thapsigargin |
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| prefixIRI |
CHEBI:9516 |
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| prefLabel |
thapsigargin |
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_37667 http://purl.obolibrary.org/obo/CHEBI_50477 |