Preferred Name |
diazoxide |
|
Synonyms |
Proglycem |
|
Definitions |
Any condition in which the main influencing factor is diazoxide, a benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. |
|
ID |
http://purl.obolibrary.org/obo/XCO_0000669 |
|
created_by |
slaulede |
|
creation_date |
2020-03-05T14:07:13Z |
|
database_cross_reference |
CHEBI:4495 |
|
definition |
Any condition in which the main influencing factor is diazoxide, a benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. |
|
has_exact_synonym |
Proglycem |
|
has_obo_namespace |
experimental_condition_ontology |
|
id |
XCO:0000669 |
|
label |
diazoxide |
|
notation |
XCO:0000669 |
|
prefLabel |
diazoxide |
|
treeView | ||
subClassOf |