loading...| Preferred Name |
Ipratropium bromide |
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| Synonyms |
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| ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass9f489f65_ce60_4295_a138_b1f31e923e5f |
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| Chinese |
异丙托溴铵 |
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| label |
Ipratropium bromide |
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| NCIt_Definition |
The bromide salt form of ipratropium, a synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic, postganglionic, effector-cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation. |
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| prefLabel |
Ipratropium bromide |
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| Synonyms |
Ipratropium bromide (substance) Ipratropium bromide Atrovent bromuro de ipratropio Ipratropium Bromide Monohydrate Ipratropium Bromide Hydrate Atrovent HFA (8R)-3alpha-Hydroxy-8-isopropyl-1alpha H5alphaH-tropanium Bromide (+-)-tropate Monohydrate |
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