Oral contraceptives

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口服避孕药

Oral contraceptives

Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.

An agent taken orally to prevent conception.

The progestogen[23]-only pill is not recommended as reliable contraception in women and girls taking enzyme-inducing AEDs.[2004, amended 2012] 不建议将仅含孕激素 [23] 的药作为服用酶诱导型抗癫痫药的妇女和女孩的可靠避孕方法。[2004 年，2012 年修订] nice.org.uk/guidance/cg137

Oral contraceptives

[GRADES OF RECOMMENDATION:C] Women should be counselled that the efficacy of oral contraceptives (combined hormonal contraception, progestogen-only pills), transdermal patches, vaginal ring and progestogen-only implants may be affected if they are taking enzyme-inducing AEDs (e.g. carbamazepine, phenytoin, phenobarbital, primidone, oxcarbazepine and eslicarbazepine). 【推荐等级：C】如果WWE正在服用酶诱导AEDs，应告知患者口服避孕药（联合激素类避孕药、仅含孕激素的药片）、透皮贴片（transdermal patches）、阴道环和仅含孕激素皮下埋植（progestogen-only implants）的疗效会受到影响。 https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/epilepsy-in-pregnancy-green-top-guideline-no-68/

Progesterone-only oral contraception, which is often the contraceptive method of choice in women who are breastfeeding, is contraindicated postpartum in women with epilepsy taking hepatic enzyme-inducing AEDs as these increase progesterone metabolism. 纯黄体酮口服避孕药通常是哺乳期妇女首选的避孕方法，但使用酶诱导AEDs的癫痫患者产后禁忌使用这种避孕药。 Scottish Intercollegiate Guidelines Network.Diagnosis and management of epilepsy in adults. SIGN 143. Edinburgh, SIGN, 2015. Available at: www.sign.ac.uk/guidelines/fulltext/143/index.html

[GRADES OF RECOMMENDATION:C] To minimise the risk of contraceptive failure, a woman using any combined hormonal contraception, or a combined oral contraceptive pill, or a progesterone-only pill should be prescribed an antiepileptic drug that does not induce hepatic enzymes. C级推荐：为避免将避孕失败的风险降到最低，使用联合避孕药、合用多种口服避孕药或仅服用黄体酮避孕药的妇女，应使用非肝酶诱导性AEDs。 Scottish Intercollegiate Guidelines Network.Diagnosis and management of epilepsy in adults. SIGN 143. Edinburgh, SIGN, 2015. Available at: www.sign.ac.uk/guidelines/fulltext/143/index.html

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