Preferred Name |
Metoprolol |
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Synonyms |
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ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass71450375_f355_49fe_8672_370bba9110a0 |
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Chinese |
美托洛尔 |
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MESH_Definition |
A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS. |
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NCIt_Definition |
A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion. |
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prefLabel |
Metoprolol |
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Synonyms |
(RS)-Metoprolol Product containing metoprolol (medicinal product) Metoprolol 2-Propanol 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)- (+-)- 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol DL-metoprolol Metoprolol-containing product Metoprolol (substance) |
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subClassOf |