Preferred Name |
Diazepam |
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Synonyms |
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ID |
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass527a5c1b_902a_464d_a04a_368e9460792f |
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China_guidence |
China_guidence 分娩:应当由产科医师与癫痫专科医师共同诊疗妊娠的癫痫患者。大部分癫痫产妇都能正常分娩,但是疼痛、压力、睡眠不足、过度换气等因素都增加了分娩期发作的危险;建议应当在配备有孕妇及新生儿复苏条件,以及紧急处理母亲癫痫发作的相应专业人士、设备的产科监护室内进行;分娩过程中及分娩后应该按时、按量服用AEDs,如果不能及时口服AEDs,应该通过其他途径给予足量AEDs;在分娩过程中,一旦出现癫痫发作,应该尽快采取措施终止发作,可选用地西泮或劳拉西泮静脉注射;如果发作持续,应该按照癫痫持续状态处理;同时采取措施尽快结束分娩,并作好新生儿抢救准备。 Li, S. and Hong, Z., 2015. Lin chuang zhen liao zhi nan. Beijing: Ren min wei sheng chu ban she. |
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Chinese |
地西泮 |
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label |
Diazepam |
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MESH_Definition |
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity. |
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NCIt_Definition |
A benzodiazepine derivative with anti-anxiety, sedative, hypnotic and anticonvulsant properties. Diazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic system and the hypothalamus. This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability. |
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prefLabel |
Diazepam |
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SIGN_Guidance |
If there is doubt whether a seizure in labour is due to eclampsia or epilepsy, a slow intravenous bolus of 4 g magnesium sulphate over five minutes followed by 1 g/hour for 24 hours is recommended in addition to midazolam, lorazepam or diazepam. 如果不能明确分娩过程中的痫性发作是由子痫引起还是由癫痫引起,建议在米达唑仑、劳拉西泮或地西泮的基础上,5min内缓慢静注硫酸镁4g,之后1g/h,持续24h。 Scottish Intercollegiate Guidelines Network.Diagnosis and management of epilepsy in adults. SIGN 143. Edinburgh, SIGN, 2015. Available at: www.sign.ac.uk/guidelines/fulltext/143/index.html |
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Synonyms |
Diazemuls Relanium Seduxen Sibazon Apaurin Faustan Stesolid diazepam Valium Diazepam-containing product Diazepam (substance) 7-chloro-13-dihydro-1-methyl-5-phenyl-2H-14-benzodiazepin-2-one Methyl diazepinone Product containing diazepam (medicinal product) 2H-14-Benzodiazepin-2-one 7-chloro-13-dihydro-1-methyl-5-phenyl- |
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subClassOf |