Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Muscle fibrillation

Synonyms

EMG: fibrillations on electromyogram

Twitching

Definitions

Fine, rapid twitching of individual muscle fibers with little or no movement of the muscle as a whole. If a motor neuron or its axon is destroyed, the muscle fibers it innervates undergo denervation atrophy. This leads to hypersensitivity of individual muscle fibers to acetyl choline so that they may contract spontaneously. Isolated activity of individual muscle fibers is generally so fine it cannot be seen through the intact skin, although it can be recorded as a short-duration spike in the EMG.

ID

http://purl.obolibrary.org/obo/HP_0010546

creation date

2009-09-29T08:23:48Z

creator

https://orcid.org/0000-0002-0736-9199

database_cross_reference

SNOMEDCT_US:41405005

UMLS:C0231531

definition

Fine, rapid twitching of individual muscle fibers with little or no movement of the muscle as a whole. If a motor neuron or its axon is destroyed, the muscle fibers it innervates undergo denervation atrophy. This leads to hypersensitivity of individual muscle fibers to acetyl choline so that they may contract spontaneously. Isolated activity of individual muscle fibers is generally so fine it cannot be seen through the intact skin, although it can be recorded as a short-duration spike in the EMG.

has exact synonym

EMG: fibrillations on electromyogram

has related synonym

Twitching

id

HP:0010546

label

Muscle fibrillation

notation

HP:0010546

prefLabel

Muscle fibrillation

subClassOf

http://purl.obolibrary.org/obo/MP_0001388

http://purl.obolibrary.org/obo/HP_0100022

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