Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Metabolic acidosis

Synonyms
Definitions

The Henderson-Hasselbalch method defines metabolic acidosis by the presence of an acid-base imbalance associated with a plasma bicarbonate concentration below 20 mmol/L. The association of this imbalance with decreased pH is called acidemia, which is often described as severe when the pH is equal to or below 7.20. Arterial blood gas measurements can be performed in patients with a decreased plasma bicarbonate level so as to eliminate respiratory alkalosis, confirm the diagnosis of metabolic acidosis, and test for mixed acidosis. Metabolic acidosis (MA) is characterized by a fall in blood pH due to a reduction of serum bicarbonate concentration. This can occur as a result of either the accumulation of acids (high anion gap MA) or the loss of bicarbonate from the gastrointestinal tract or the kidney (hyperchloremic MA). By definition, MA is not due to a respirary cause.

ID

http://purl.obolibrary.org/obo/HP_0001942

comment

The Henderson-Hasselbalch method defines metabolic acidosis by the presence of an acid-base imbalance associated with a plasma bicarbonate concentration below 20 mmol/L. The association of this imbalance with decreased pH is called acidemia, which is often described as severe when the pH is equal to or below 7.20. Arterial blood gas measurements can be performed in patients with a decreased plasma bicarbonate level so as to eliminate respiratory alkalosis, confirm the diagnosis of metabolic acidosis, and test for mixed acidosis.

database_cross_reference

MSH:D000138

UMLS:C0220981

SNOMEDCT_US:59455009

definition

Metabolic acidosis (MA) is characterized by a fall in blood pH due to a reduction of serum bicarbonate concentration. This can occur as a result of either the accumulation of acids (high anion gap MA) or the loss of bicarbonate from the gastrointestinal tract or the kidney (hyperchloremic MA). By definition, MA is not due to a respirary cause.

equivalentClass

http://purl.obolibrary.org/obo/MP_0012551

has_alternative_id

HP:0004895

HP:0004907

id

HP:0001942

label

Metabolic acidosis

notation

HP:0001942

prefLabel

Metabolic acidosis

subClassOf

http://purl.obolibrary.org/obo/MP_0003031

http://purl.obolibrary.org/obo/HP_0001941

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/HP_0001942 MONDO SAME_URI
http://purl.obolibrary.org/obo/HP_0001942 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0001942 DIAB SAME_URI
http://purl.obolibrary.org/obo/HP_0001942 EUPATH SAME_URI
http://purl.obolibrary.org/obo/HP_0001942 HP SAME_URI
http://purl.obolibrary.org/obo/HP_0001942 KTAO SAME_URI
http://purl.obolibrary.org/obo/MONDO_0000440 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0000440 EFO LOOM
http://purl.obolibrary.org/obo/HP_0001942 EFO LOOM
http://purl.obolibrary.org/obo/MP_0012551 MP LOOM
http://purl.obolibrary.org/obo/DOID_0050758 DOID LOOM
http://www.semanticweb.org/ontologies/2012/5/Ontology1338526551855.owl#Metabolic_acidosis RPO LOOM
http://purl.obolibrary.org/obo/MONDO_0000440 CCONT LOOM
http://purl.obolibrary.org/obo/MONDO_0000440 HSPO LOOM
http://purl.obolibrary.org/obo/MONDO_0000440 DOVES LOOM
http://purl.bioontology.org/ontology/MEDDRA/10027417 MEDDRA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28228 NCIT LOOM
http://www.gamuts.net/entity#metabolic_acidosis GAMUTS LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01201 MIO LOOM
http://id.nlm.nih.gov/mesh/D000138 MDM LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/59455009 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0220981 OCHV LOOM
http://purl.obolibrary.org/obo/MP_0012551 CHIRO LOOM
http://www.co-ode.org/ontologies/galen#MetabolicAcidosis GALEN LOOM
http://www.icn.ch/icnp#MetabolicAcidosis ICNP LOOM
http://bmi.utah.edu/ontologies/hfontology/C0220981 HFO LOOM
http://purl.obolibrary.org/obo/HP_0001942 DIAB LOOM
http://purl.obolibrary.org/obo/HP_0001942 EUPATH LOOM
http://purl.obolibrary.org/obo/HP_0001942 HP LOOM
http://purl.obolibrary.org/obo/HP_0001942 KTAO LOOM
http://purl.obolibrary.org/obo/NCIT_C28228 BERO LOOM
http://purl.obolibrary.org/obo/DOID_0050758 HTN LOOM
http://purl.obolibrary.org/obo/DOID_0050758 DTO LOOM
http://purl.obolibrary.org/obo/DOID_0050758 BAO LOOM
http://purl.obolibrary.org/obo/DOID_0050758 HHEAR LOOM
http://purl.obolibrary.org/obo/DOID_0050758 NIFSTD LOOM
http://purl.obolibrary.org/obo/DOID_0050758 FNS-H LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU036658 OMIM LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Metabolic_Acidosis CSEO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00003622 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RCD/X40PT RCD LOOM