Combined Phenotype Ontology

Last uploaded: November 18, 2021
Preferred Name

Nevus flammeus

Synonyms

Nevus simplex

port-wine stain

Definitions

A congenital vascular malformation consisting of superficial and deep dilated capillaries in the skin which produce a reddish to purplish discolouration of the skin. Port-wine stains generally become deeper, thicker, and darker in color over time, mainly as a result of progressive vascular dilatation. As a result of these changes, which are generally much more evident on the face, patients often develop hypertrophy and nodularity after the third or fourth decade of life. The fact that nodules are only found on the face and do not occur in childhood has led some authors to suggest that port-wine stains might actually be hamartomatous lesions.

ID

http://purl.obolibrary.org/obo/HP_0001052

comment

Port-wine stains generally become deeper, thicker, and darker in color over time, mainly as a result of progressive vascular dilatation. As a result of these changes, which are generally much more evident on the face, patients often develop hypertrophy and nodularity after the third or fourth decade of life. The fact that nodules are only found on the face and do not occur in childhood has led some authors to suggest that port-wine stains might actually be hamartomatous lesions.

database_cross_reference

SNOMEDCT_US:416377005

UMLS:C0235752

SNOMEDCT_US:254211001

MSH:D019339

MEDDRA:10067193

definition

A congenital vascular malformation consisting of superficial and deep dilated capillaries in the skin which produce a reddish to purplish discolouration of the skin.

has exact synonym

Nevus simplex

port-wine stain

id

HP:0001052

in_subset

http://purl.obolibrary.org/obo/hp#hposlim_core

label

Nevus flammeus

notation

HP:0001052

prefLabel

Nevus flammeus

subClassOf

http://purl.obolibrary.org/obo/HP_0025104

http://purl.obolibrary.org/obo/HP_0003764

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