loading...| Preferred Name | maraviroc | |
| Synonyms |
maraviroc maravirocum 4,4-difluoro-N-{(1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide |
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| Definitions |
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4,4-difluorocyclohexanecarboxylic acid and the primary amino group of (1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropylamine. An antiretroviral drug, it prevents the interaction of HIV-1 gp120 and chemokine receptor 5 (CCR5) necessary for CCR5-tropic HIV-1 to enter cells. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_63608 |
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| database_cross_reference |
DrugBank:DB04835 PMID:22247337 PMID:21987241 PMID:25017682 PMID:22034870 PMID:24651825 PMID:22174038 PMID:24419064 PMID:21134404 Reaxys:10131963 PMID:22064539 PMID:21595497 PMID:21692669 CAS:376348-65-1 PMID:22236118 PMID:24652492 PMID:21505306 PMID:21393136 PMID:21383098 PMID:22090117 PMID:22118500 PMID:22017448 |
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| definition |
A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4,4-difluorocyclohexanecarboxylic acid and the primary amino group of (1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropylamine. An antiretroviral drug, it prevents the interaction of HIV-1 gp120 and chemokine receptor 5 (CCR5) necessary for CCR5-tropic HIV-1 to enter cells. |
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| has role |
http://purl.obolibrary.org/obo/CHEBI_59886 |
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| has_exact_synonym |
4,4-difluoro-N-{(1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide |
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| has_related_synonym |
maraviroc maravirocum |
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| id |
CHEBI:63608 |
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| label |
maraviroc |
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| notation |
CHEBI:63608 |
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| prefLabel |
maraviroc |
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| subClassOf |