loading...| Preferred Name |
gemcitabine |
|
| Synonyms |
2'-deoxy-2',2'-difluorocytidine gemcitabina gemcitabine gemcitabinum 2',2'-Difluorodeoxycytidine 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 2'-Deoxy-2',2'-difluorocytidine |
|
| Definitions |
A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_175901 |
|
| database_cross_reference |
PMID:22763439 PMID:11510027 PMID:28608357 PMID:16905983 PMID:17987263 PMID:17296587 PMID:19399788 PMID:17941128 PMID:17602464 PMID:18186604 PMID:15542781 PMID:12917815 PMID:11122828 PMID:11221019 PMID:17296311 PMID:16317298 PMID:11374818 Beilstein:5382060 LINCS:LSM-5333 PMID:16807463 PMID:18348652 PMID:12722691 PMID:12798170 PMID:28594276 PMID:18789834 PMID:19839926 PMID:11142482 PMID:12761494 PMID:12115355 PMID:18773046 PMID:17347561 PMID:12057041 PMID:17639396 PMID:11901308 PMID:15131028 PMID:17939651 PMID:16584929 PMID:16143373 PMID:12743987 PMID:19879060 PMID:11356111 PMID:16080557 DrugBank:DB00441 PMID:16041610 PMID:12057157 PMID:17887663 PMID:12520460 Drug_Central:1283 Reaxys:5382060 PMID:11061612 PMID:16894289 PMID:17101674 PMID:16149285 PMID:11489002 PMID:11088063 PMID:18257544 PMID:11859947 PMID:11585734 PMID:14720338 PMID:14653877 PMID:28912244 PMID:11504793 PMID:19177022 PMID:12571808 PMID:18050344 PMID:11132538 PMID:14606642 PMID:12722678 PMID:18035967 PMID:12057046 PMID:15297392 PMID:11807603 PMID:17429628 PMID:16001951 PMID:16807461 PMID:15282439 PMID:18086345 PMID:16500746 CAS:95058-81-4 PMID:15744590 PMID:11034044 PMID:16555971 PMID:12142097 PMID:18166944 PMID:17460420 PMID:15637766 PMID:15160243 PMID:18981552 PMID:15221904 PMID:11595724 PMID:19034448 PMID:12954073 PMID:18819792 |
|
| definition |
A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_47868 http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_59517 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_74213 http://purl.obolibrary.org/obo/CHEBI_132992 http://purl.obolibrary.org/obo/CHEBI_36044 |
|
| has_exact_synonym |
2'-deoxy-2',2'-difluorocytidine |
|
| has_related_synonym |
gemcitabina gemcitabine gemcitabinum 2',2'-Difluorodeoxycytidine 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 2'-Deoxy-2',2'-difluorocytidine |
|
| id |
CHEBI:175901 |
|
| label |
gemcitabine |
|
| notation |
CHEBI:175901 |
|
| prefLabel |
gemcitabine |
|
| subClassOf |