The Stroke Ontology

Last uploaded: August 7, 2018

Preferred Name	Lipoprotein associated phospholipase A2
Synonyms
Definitions	Biomarkers of ischemic stroke
ID	http://www.semanticweb.org/ontologies/STO.owl#OWLClass_1787fb85_547f_40d6_9b60_c3f5eb5d8003
comment	Biomarkers of ischemic stroke
hasDbXref	http://purl.bioontology.org/ontology/OMIM/601690 http://purl.bioontology.org/ontology/MESH/D043203
isDefinedBy	A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
label	Lipoprotein associated phospholipase A2
prefixIRI	OWLClass_1787fb85_547f_40d6_9b60_c3f5eb5d8003
prefLabel	Lipoprotein associated phospholipase A2
source	http://purl.bioontology.org/ontology/MESH/D043203
synonyms	Platelet-activating factor acetylhydrolase LDL-associated phospholipase A2 PAF acetylhydrolase Lipoprotein-associated phospholipase A2 LDL-PLA2 Lp-PLA2 PLA2G7
subClassOf	http://www.semanticweb.org/ontologies/STO.owl#OWLClass_797fe22f_ad66_4f67_9fe8_c20d3d796e36

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Mapping To	Ontology	Source
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_1787fb85_547f_40d6_9b60_c3f5eb5d8003	CVAO	SAME_URI
http://purl.bioontology.org/ontology/MEDDRA/10083082	MEDDRA	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU018220	LOINC	LOOM
http://www.ustb.edu.cn/thesauri/tocr/v1/data#C571347974240596158	ACVD_ONTOLOGY	LOOM
http://purl.bioontology.org/ontology/LNC/LP35390-1	LOINC	LOOM
http://purl.jp/bio/4/id/201306029408211406	IOBC	LOOM
http://www.semanticweb.org/ontologies/STO.owl#OWLClass_1787fb85_547f_40d6_9b60_c3f5eb5d8003	CVAO	LOOM