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SNOMED CT
| Preferred Name | Autoimmune hemolytic anemia mixed type | |
| Synonyms |
Autoimmune hemolytic anemia mixed type (disorder) Autoimmune haemolytic anaemia mixed type |
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| Definitions |
Mixed autoimmune hemolytic anemia (mixed AIHA) is a type of autoimmune hemolytic anemia defined by the presence of both warm and cold autoantibodies, which have a deleterious effect on red blood cells at either body temperature or at lower temperatures. Diagnosis is based on clinical or laboratory evidence of hemolytic anemia and the detection of autoantibodies, usually both IgG and IgM, with the direct anti-globulin test (DAT) showing a pattern of IgG with complement C3, and the presence of cold agglutinins (IgM) in the serum at a significant titer. The disease responds to corticosteroids, and may be followed by remission, but usually runs a chronic course with intermittent exacerbations. Mixed autoimmune haemolytic anaemia (mixed AIHA) is a type of autoimmune haemolytic anaemia defined by the presence of both warm and cold autoantibodies, which have a deleterious effect on red blood cells at either body temperature or at lower temperatures. Diagnosis is based on clinical or laboratory evidence of haemolytic anaemia and the detection of autoantibodies, usually both IgG and IgM, with the direct anti-globulin test (DAT) showing a pattern of IgG with complement C3, and the presence of cold agglutinins (IgM) in the serum at a significant titre. The disease responds to corticosteroids, and may be followed by remission, but usually runs a chronic course with intermittent exacerbations. |
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| ID |
http://purl.bioontology.org/ontology/SNOMEDCT/718716008 |
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| Active |
1
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| altLabel |
Autoimmune hemolytic anemia mixed type (disorder) Autoimmune haemolytic anaemia mixed type
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| CASE SIGNIFICANCE ID |
900000000000448009
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| CTV3ID |
XUts4
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| cui |
C4305257
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| definition |
Mixed autoimmune hemolytic anemia (mixed AIHA) is a type of autoimmune hemolytic anemia defined by the presence of both warm and cold autoantibodies, which have a deleterious effect on red blood cells at either body temperature or at lower temperatures. Diagnosis is based on clinical or laboratory evidence of hemolytic anemia and the detection of autoantibodies, usually both IgG and IgM, with the direct anti-globulin test (DAT) showing a pattern of IgG with complement C3, and the presence of cold agglutinins (IgM) in the serum at a significant titer. The disease responds to corticosteroids, and may be followed by remission, but usually runs a chronic course with intermittent exacerbations. Mixed autoimmune haemolytic anaemia (mixed AIHA) is a type of autoimmune haemolytic anaemia defined by the presence of both warm and cold autoantibodies, which have a deleterious effect on red blood cells at either body temperature or at lower temperatures. Diagnosis is based on clinical or laboratory evidence of haemolytic anaemia and the detection of autoantibodies, usually both IgG and IgM, with the direct anti-globulin test (DAT) showing a pattern of IgG with complement C3, and the presence of cold agglutinins (IgM) in the serum at a significant titre. The disease responds to corticosteroids, and may be followed by remission, but usually runs a chronic course with intermittent exacerbations.
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| DEFINITION STATUS ID |
900000000000074008
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| Effective time |
20170131
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| Has causative agent | ||
| Has clinical course | ||
| Has interpretation | ||
| Has pathological process | ||
| interprets | ||
| notation |
718716008
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| Occurs in | ||
| prefLabel |
Autoimmune hemolytic anemia mixed type
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| Subset member |
447562003~MAPRULE~TRUE 447562003~MAPTARGET~D59.1 6011000124106~MAPGROUP~1 447562003~MAPGROUP~1 447562003~CORRELATIONID~447561005 6011000124106~MAPCATEGORYID~447637006 6011000124106~MAPADVICE~ALWAYS D59.1 900000000000509007~ACCEPTABILITYID~900000000000548007 900000000000508004~ACCEPTABILITYID~900000000000548007 6011000124106~MAPADVICE~ALWAYS D59.13 6011000124106~MAPTARGET~D59.1 447562003~MAPPRIORITY~1 447562003~MAPCATEGORYID~447637006 6011000124106~MAPRULE~OTHERWISE TRUE 6011000124106~MAPCATEGORYID~447639009 6011000124106~MAPPRIORITY~1 6011000124106~MAPTARGET~D59.13 6011000124106~CORRELATIONID~447561005 6011000124106~MAPRULE~IFA 445518008 | Age at onset of clinical finding (observable entity) | < 29.0 days 900000000000497000~MAPTARGET~XUts4 447562003~MAPADVICE~ALWAYS D59.1 6011000124106~MAPPRIORITY~2 6011000124106~MAPTARGET~P55.8 6011000124106~MAPADVICE~IF AGE AT ONSET OF CLINICAL FINDING BEFORE 29.0 DAYS CHOOSE P55.8 | MAP OF SOURCE CONCEPT IS CONTEXT DEPENDENT
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| tui |
T047
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| Type ID |
900000000000003001 900000000000013009
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| subClassOf |
http://purl.bioontology.org/ontology/SNOMEDCT/398937006 http://purl.bioontology.org/ontology/SNOMEDCT/3978000 |
| Delete | Subject | Author | Type | Created |
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| No notes to display |
| Mapping To | Ontology | Source |
|---|---|---|
| http://purl.bioontology.org/ontology/SCTSPA/718716008 | SCTSPA | CUI |
| http://purl.bioontology.org/ontology/ICD10CM/D59.13 | ICD10CM | CUI |