Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Troponin T

Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Troponin_T

definition

Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury.

label

Troponin T

prefixIRI

Troponin_T

prefLabel

Troponin T

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38041

Synonyms

TNNT Troponin T

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cytoskeletal_Protein

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Paediatric_Sepsis_Prognostic_Biomarker

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