Preferred Name |
Troponin T |
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Synonyms |
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ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Troponin_T |
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definition |
Troponin I, troponin T, and troponin C are the three closely associated subunits of the troponin complex of thin filaments in muscle. The complex serves as a calcium-sensitive switch that regulates muscle contraction. Troponin T binds tropomyosin to the troponin complex and inhibits F-actin-myosin interactions. The troponin T gene family comprises three isoforms: slow skeletal (TNNT1), cardiac (TNNT2) and fast skeletal (TNNT3). Because it is not normally found in blood, cardiac troponin-T in serum is a sensitive indicator of myocardial cell injury. |
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label |
Troponin T |
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prefixIRI |
Troponin_T |
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prefLabel |
Troponin T |
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reference | ||
Synonyms |
TNNT Troponin T |
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subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cytoskeletal_Protein |