Link to this page
Sepsis Ontology
Last uploaded:
May 14, 2024
Jump to:
Preferred Name | Ticagrelor | |
Synonyms |
|
|
ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ticagrelor |
|
definition |
An orally bioavailable cyclopentyltriazolopyrimidine, with antiplatelet activity. Upon oral administration, ticagrelor and its major metabolite targets and reversibly binds to the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R) at a site distinct from that of the endogenous agonist ADP. This blocks the platelet signaling pathway, thereby inhibiting the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation.
|
|
label |
Ticagrelor
|
|
prefixIRI |
Ticagrelor
|
|
prefLabel |
Ticagrelor
|
|
reference | ||
Synonyms |
Thioxlant-6C
AR-C126532XX
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
AZD6140
Brilinta
Brilique
TICAGRELOR
Ticagrelor
Ticalog
|
|
subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#P2Y12_Inhibitor |
Add comment
Delete | Subject | Author | Type | Created |
---|---|---|---|---|
No notes to display |
Create mapping