Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Ticagrelor
Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ticagrelor

definition

An orally bioavailable cyclopentyltriazolopyrimidine, with antiplatelet activity. Upon oral administration, ticagrelor and its major metabolite targets and reversibly binds to the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R) at a site distinct from that of the endogenous agonist ADP. This blocks the platelet signaling pathway, thereby inhibiting the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation.

label

Ticagrelor

prefixIRI

Ticagrelor

prefLabel

Ticagrelor

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76404

Synonyms

Thioxlant-6C AR-C126532XX (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol AZD6140 Brilinta Brilique TICAGRELOR Ticagrelor Ticalog

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#P2Y12_Inhibitor

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_68558 DRON LOOM
http://purl.bioontology.org/ontology/NDDF/013611 NDDF LOOM
http://purl.bioontology.org/ontology/RXNORM/1116632 RXNORM LOOM
http://purl.bioontology.org/ontology/LNC/LA26705-6 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_68558 DDSS LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025417 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C76404 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000182973 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4030908 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D000077486 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C503700 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C76404 NCIT LOOM
http://www.drugbank.ca/drugs/DB08816 FTC LOOM
http://purl.bioontology.org/ontology/ATC/B01AC24 ATC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/698805004 SNOMEDCT LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01071 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01071 MIO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01071 MIO LOOM
http://purl.jp/bio/4/id/201206086339362991 IOBC LOOM
https://go.drugbank.com/drugs/DB08816 MDM LOOM
http://stirdf.jst.go.jp/id/200907061156974772 IOBC LOOM