Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Nuclear Receptor

Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Nuclear_Receptor

definition

Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity.

label

Nuclear Receptor

prefixIRI

Nuclear_Receptor

prefLabel

Nuclear Receptor

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17671

Synonyms

Receptor, Nuclear Nuclear Receptor

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Receptor

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