loading...| Preferred Name | Itraconazole | |
| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Itraconazole |
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| definition |
A synthetic triazole agent with antimycotic properties. Formulated for both topical and systemic use, itraconazole preferentially inhibits fungal cytochrome P450 enzymes, resulting in a decrease in fungal ergosterol synthesis. Because of its low toxicity profile, this agent can be used for long-term maintenance treatment of chronic fungal infections. |
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| label |
Itraconazole |
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| prefixIRI |
Itraconazole |
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| prefLabel |
Itraconazole |
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| reference | ||
| Synonyms |
Oriconazole (+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup2)-1,2,4-triazolin-5-one itraconazole Itraconazole ITRACONAZOLE Lozanoc R 51,211 Sporanox |
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antifungal_Agent |