loading...| Preferred Name |
Interferon |
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| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Interferon |
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| definition |
Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. |
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| label |
Interferon |
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| prefixIRI |
Interferon |
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| prefLabel |
Interferon |
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| reference | ||
| Synonyms |
Human Fibroblast Interferon Human Lymphoblastoid Interferon Human Leukocyte Interferon IFN Interferon interferon |
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cytokine http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antiviral_Agent |