loading...| Preferred Name |
Emtricitabine |
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| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Emtricitabine |
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| definition |
A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group). |
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| label |
Emtricitabine |
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| prefixIRI |
Emtricitabine |
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| prefLabel |
Emtricitabine |
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| reference | ||
| Synonyms |
2(1H)-Pyrimidinone,4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-Emtricitabine EMTRICITABINE (-)-2'-Deoxy-5-fluoro-3'-thiacytidine BW-524W91 Coviracil Emtriva FTC dOTFC |
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