Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Efavirenz
Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Efavirenz

definition

A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity. Efavirenz binds directly to the human immunodeficiency virus type 1 (HIV-1) RT, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce HIV viral load, retarding or preventing damage to the immune system and reducing the risk of developing AIDS. Efavirenz induces activity of the cytochrome P450 system, accelerating its own metabolism.

label

Efavirenz

prefixIRI

Efavirenz

prefLabel

Efavirenz

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29027

Synonyms

DMP-266 EFAVIRENZ Efavirenz L743726 MK-0831 Sustiva efavirenz

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Non-nucleoside_Reverse_Transcriptase_Inhibitor

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http://purl.obolibrary.org/obo/CHEBI_119486 OBA LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148587 NDFRT LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 HUPSON LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_119486 CHEBI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29027 NCIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000540650 PDQ LOOM
http://purl.jp/bio/4/id/200906045925420948 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Efavirenz GALEN LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148587 ODAE LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0674428 OCHV LOOM
http://stirdf.jst.go.jp/id/200907063104639153 IOBC LOOM
https://go.drugbank.com/drugs/DB00625 MDM LOOM
http://purl.obolibrary.org/obo/DRON_00017693 ODNAE LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#42573 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/C098320 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026003 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387001004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/195085 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C098320 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C29027 BERO LOOM
http://purl.bioontology.org/ontology/LNC/LP21310-5 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013845 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/5000-0023 CRISP LOOM
http://purl.bioontology.org/ontology/VANDF/4021133 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/J05AG03 ATC LOOM