loading...| Preferred Name |
Dirithromycin |
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| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Dirithromycin |
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| definition |
A semi-synthetic macrolide antibiotic pro-drug. Dirithromycin is converted by hydrolysis during intestinal absorption into the microbiologically active erythromycylamine. Eryhtromylamine binds to the 50 S subunit of the 70 S ribosome of susceptible organisms, thereby inhibiting bacterial RNA-dependent protein synthesis. This antibiotic is used in the treatment of infections of the respiratory tract, skin and soft tissue caused by gram-positive microorganisms, including S. aureus, S. pneumonia and pyogenes, gram-negative microorganisms, including H. influenzae, L. pneumophila, M. catarrhalis, and M. pneumoniae. |
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| label |
Dirithromycin |
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| prefixIRI |
Dirithromycin |
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| prefLabel |
Dirithromycin |
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| reference | ||
| Synonyms |
DIRITHROMYCIN Dirithromycin Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-,(9S(R))- Dynabac |
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Macrolide_Antibiotic |