Sickle Cell Disease Ontology

Last uploaded: May 6, 2021
Preferred Name

Acute Tubular Necrosis

Synonyms

Renal Tubular Necrosis

ATN

Definitions

Acute death of renal tubular cells that usually results from prolonged renal ischemia, nephrotoxins, or sepsis.

ID

http://purl.obolibrary.org/obo/HP_0008682

curator note

Provide source for additional info.

database cross reference

HP:0008682

definition

Acute death of renal tubular cells that usually results from prolonged renal ischemia, nephrotoxins, or sepsis.

definition source

http://purl.obolibrary.org/obo/HP_0008682

diagnosed using measurement

http://purl.obolibrary.org/obo/CMO_0000057

existence in other ontologies

Sufficient

has age of onset

Can occur at any age.

has disease stage

The clinical course of acute tubular necrosis may be divided into initiation, maintenance, and recovery phases.

hasExactSynonym

Renal Tubular Necrosis

ATN

in guideline

http://purl.obolibrary.org/obo/SCDO_1000147

is caused by

Renal ischemia (which can occur due to prolonged prerenal states), nephrotoxins, or sepsis. In sickle cell disease, may occur due to renal ischemia related to sickle crisis.

is characterised by

Loss of kidney function, reduced urine output, elevated serum creatinine.

prefixIRI

HP:0008682

prefLabel

Acute Tubular Necrosis

previous identifier

SCDO:0000020

rdfs:label

Acute Tubular Necrosis

skos:prefLabel

Acute Tubular Necrosis

treated with

http://purl.obolibrary.org/obo/SCDO_0001129

http://purl.obolibrary.org/obo/SCDO_0000983

subClassOf

http://purl.obolibrary.org/obo/SCDO_1000000

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