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Pathway Ontology
Last uploaded:
October 21, 2024
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| Preferred Name | tumor necrosis factor superfamily mediated signaling pathway | |
| Synonyms |
TNF superfamily mediated signaling pathway |
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| Definitions |
Members of TNF superfamily mediate autoimmunity and inflammation, cell proliferation, survival and/or apoptosis through a number of signaling mechanisms that involve activation of nuclear factor-kappaB, of caspases and/or of mitogen-activated protein kinases (MAPK). TNF superfamily has been implicated in a wide range of human diseases including tumorigenesis, septic shock, rheumatoid arthritis and other conditions. |
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| ID |
http://purl.obolibrary.org/obo/PW_0000236 |
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| definition |
Members of TNF superfamily mediate autoimmunity and inflammation, cell proliferation, survival and/or apoptosis through a number of signaling mechanisms that involve activation of nuclear factor-kappaB, of caspases and/or of mitogen-activated protein kinases (MAPK). TNF superfamily has been implicated in a wide range of human diseases including tumorigenesis, septic shock, rheumatoid arthritis and other conditions.
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| has_obo_namespace |
pathway
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| has_related_synonym |
TNF superfamily mediated signaling pathway
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| id |
PW:0000236
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| label |
tumor necrosis factor superfamily mediated signaling pathway
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| notation |
PW:0000236
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| prefLabel |
tumor necrosis factor superfamily mediated signaling pathway
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| treeView | ||
| subClassOf |
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