Pathway Ontology

Last uploaded: October 21, 2024
Preferred Name

extrinsic apoptotic pathway
Synonyms

death receptor mediated apoptotic pathway

Caspase activation via extrinsic apoptotic signalling pathway

extrinsic apoptotic signaling pathway

Definitions

The apoptotic pathway involving the death receptors-mediated route of caspase activation. Members of the tumor necrosis superfamily such as the better known Tnf-alpha (Tnf), Fas ligand or Trail elicit apoptosis via receptor-associated adapters.

ID

http://purl.obolibrary.org/obo/PW_0000106

definition

The apoptotic pathway involving the death receptors-mediated route of caspase activation. Members of the tumor necrosis superfamily such as the better known Tnf-alpha (Tnf), Fas ligand or Trail elicit apoptosis via receptor-associated adapters.

has_obo_namespace

pathway

has_related_synonym

death receptor mediated apoptotic pathway

Caspase activation via extrinsic apoptotic signalling pathway

extrinsic apoptotic signaling pathway

id

PW:0000106

label

extrinsic apoptotic pathway

notation

PW:0000106

prefLabel

extrinsic apoptotic pathway

treeView

http://purl.obolibrary.org/obo/PW_0000009

subClassOf

http://purl.obolibrary.org/obo/PW_0000009

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