PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Multicellular Organism Aging
Synonyms
Definitions

"An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators]

ID

http://www.phoc.org.cn/pmo/class/PMO_00069081

Database_Cross_Reference

GO:0010259

Definition

"An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators]

Gene Annotation

CRYAB(UniProtKB:P02511)

COMP(UniProtKB:P49747)

SEC63(UniProtKB:Q9UGP8)

EDN1(UniProtKB:P05305)

TP63(UniProtKB:Q9H3D4)

NDUFS6(UniProtKB:O75380)

SLC1A2(UniProtKB:P43004)

SERP1(UniProtKB:Q9Y6X1)

DDC(UniProtKB:P20711)

CISD2(UniProtKB:Q8N5K1)

NR5A1(UniProtKB:Q13285)

HYAL2(UniProtKB:Q12891)

ERCC1(UniProtKB:P07992)

WRN(UniProtKB:Q14191)

TH(UniProtKB:P07101)

RNF165(UniProtKB:Q6ZSG1)

HELT(UniProtKB:A6NFD8)

CTSV(UniProtKB:O60911)

label

Multicellular Organism Aging

MCID

MC04789379

PMOID

PMO:00069081

prefixIRI

pmo:PMO_00069081

prefLabel

Multicellular Organism Aging

Tree Number

T10.1.7.12.181.2

T10.1.7.21.2

T10.1.25.18.2

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00069477

http://www.phoc.org.cn/pmo/class/PMO_00069066

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