loading...| Preferred Name | Aging | |
| Synonyms |
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| Definitions |
"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00069477 |
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| Database_Cross_Reference |
GO:0007568 |
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| Definition |
"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] |
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| Gene Annotation |
KMO(UniProtKB:O15229) TIMP1(UniProtKB:P01033) GRB2(UniProtKB:P62993) ENO3(UniProtKB:P13929) MT-ND4(UniProtKB:P03905) TPRA1(UniProtKB:Q86W33) POLG(UniProtKB:P54098) KRT25(UniProtKB:Q7Z3Z0) JUN(UniProtKB:P05412) BCL2A1(UniProtKB:Q16548) LOXL2(UniProtKB:Q9Y4K0) LONP1(UniProtKB:P36776) NPY2R(UniProtKB:P49146) CTNNA1(UniProtKB:P35221) TGFB1(UniProtKB:P01137) KL(UniProtKB:Q9UEF7) GNRH1(UniProtKB:P01148) IGFBP1(UniProtKB:P08833) PCK1(UniProtKB:P35558) CNR1(UniProtKB:P21554) HTRA2(UniProtKB:O43464) CANX(UniProtKB:P27824) TNFRSF1B(UniProtKB:P20333) ITGB2(UniProtKB:P05107) GNAO1(UniProtKB:P09471) BECN1(UniProtKB:Q14457) FOS(UniProtKB:P01100) TRPC6(UniProtKB:Q9Y210) CNP(UniProtKB:P09543) PPARGC1A(UniProtKB:Q9UBK2) ADRA1A(UniProtKB:P35348) NTRK1(UniProtKB:P04629) CYP1A1(UniProtKB:P04798) PTEN(UniProtKB:P60484) CAT(UniProtKB:P04040) PDGFRB(UniProtKB:P09619) GPX4(UniProtKB:P36969) HMGCR(UniProtKB:P04035) GJB2(UniProtKB:P29033) KRTAP4-8(UniProtKB:Q9BYQ9) CASP2(UniProtKB:P42575) MPO(UniProtKB:P05164) RPN2(UniProtKB:P04844) STAT3(UniProtKB:P40763) SERPING1(UniProtKB:P05155) LRP1(UniProtKB:Q07954) EIF2B5(UniProtKB:Q13144) EIF2S1(UniProtKB:P05198) DCN(UniProtKB:P07585) PAX5(UniProtKB:Q02548) ATG7(UniProtKB:O95352) P2RY1(UniProtKB:P47900) ERCC2(UniProtKB:P18074) KCNMB1(UniProtKB:Q16558) FBXO4(UniProtKB:Q9UKT5) ADA(UniProtKB:P00813) FOXO4(UniProtKB:P98177) MMP7(UniProtKB:P09237) PITX3(UniProtKB:O75364) TGFB3(UniProtKB:P10600) IGFBP5(UniProtKB:P24593) CD68(UniProtKB:P34810) KCNE2(UniProtKB:Q9Y6J6) TIMP2(UniProtKB:P16035) OGG1(UniProtKB:O15527) FOXO3(UniProtKB:O43524) KRT83(UniProtKB:P78385) TYMS(UniProtKB:P04818) GSS(UniProtKB:P48637) ABAT(UniProtKB:P80404) PENK(UniProtKB:P01210) EEF2(UniProtKB:P13639) PDE4D(UniProtKB:Q08499) GCLC(UniProtKB:P48506) SLC6A3(UniProtKB:Q01959) SCAP(UniProtKB:Q12770) PPP1R9A(UniProtKB:Q9ULJ8) NFE2L2(UniProtKB:Q16236) MAPK3(UniProtKB:P27361) NUDT1(UniProtKB:P36639) C1QA(UniProtKB:P02745) MME(UniProtKB:P08473) ALDH3A1(UniProtKB:P30838) AMFR(UniProtKB:Q9UKV5) GLRX2(UniProtKB:Q9NS18) TSPO(UniProtKB:P30536) EDNRB(UniProtKB:P24530) JUND(UniProtKB:P17535) ATP2B1(UniProtKB:P20020) GCLM(UniProtKB:P48507) TGFBR2(UniProtKB:P37173) DAG1(UniProtKB:Q14118) GJB6(UniProtKB:O95452) KRTAP4-7(UniProtKB:Q9BYR0) AGT(UniProtKB:P01019) UCP2(UniProtKB:P55851) SIRT3(UniProtKB:Q9NTG7) SNCA(UniProtKB:P37840) MBD3(UniProtKB:O95983) CACYBP(UniProtKB:Q9HB71) DNMT3A(UniProtKB:Q9Y6K1) SLC32A1(UniProtKB:Q9H598) CARM1(UniProtKB:Q86X55) APEX1(UniProtKB:P27695) HTR2A(UniProtKB:P28223) CTGF(UniProtKB:P29279) GSN(UniProtKB:P06396) IRAK1(UniProtKB:P51617) SERPINF1(UniProtKB:P36955) KRTAP4-5(UniProtKB:Q9BYR2) HAMP(UniProtKB:P81172) CX3CL1(UniProtKB:P78423) SLC12A2(UniProtKB:P55011) MBD2(UniProtKB:Q9UBB5) IL10(UniProtKB:P22301) CTSC(UniProtKB:P53634) AKT1(UniProtKB:P31749) ALOX12(UniProtKB:P18054) NPY5R(UniProtKB:Q15761) PPP3CA(UniProtKB:Q08209) MT-ATP6(UniProtKB:P00846) SIN3A(UniProtKB:Q96ST3) RGN(UniProtKB:Q15493) WRN(UniProtKB:Q14191) PAX2(UniProtKB:Q02962) POLB(UniProtKB:P06746) DNMBP(UniProtKB:Q6XZF7) IGFBP2(UniProtKB:P18065) ATP8A2(UniProtKB:Q9NTI2) NAPEPLD(UniProtKB:Q6IQ20) ARG1(UniProtKB:P05089) LITAF(UniProtKB:Q99732) CDKN1C(UniProtKB:P49918) KRT33B(UniProtKB:Q14525) NAMPT(UniProtKB:P43490) VCAM1(UniProtKB:P19320) NFKB2(UniProtKB:Q00653) ADM(UniProtKB:P35318) PTH1R(UniProtKB:Q03431) RETN(UniProtKB:Q9HD89) TACR3(UniProtKB:P29371) PTGS2(UniProtKB:P35354) ENDOG(UniProtKB:Q14249) KRTAP4-3(UniProtKB:Q9BYR4) KRT14(UniProtKB:P02533) SREBF1(UniProtKB:P36956) CLDN1(UniProtKB:O95832) KRT16(UniProtKB:P08779) SRR(UniProtKB:Q9GZT4) COL4A2(UniProtKB:P08572) IL15(UniProtKB:P40933) APAF1(UniProtKB:O14727) EPO(UniProtKB:P01588) RELA(UniProtKB:Q04206) BAK1(UniProtKB:Q16611) AURKB(UniProtKB:Q96GD4) DLD(UniProtKB:P09622) CASP9(UniProtKB:P55211) KRTAP4-9(UniProtKB:Q9BYQ8) KYNU(UniProtKB:Q16719) CREB1(UniProtKB:P16220) APOD(UniProtKB:P05090) MT-CO1(UniProtKB:P00395) FOXG1(UniProtKB:P55316) ASS1(UniProtKB:P00966) UCP3(UniProtKB:P55916) NQO1(UniProtKB:P15559) MAPK1(UniProtKB:P28482) AMH(UniProtKB:P03971) |
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| label |
Aging |
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| MCID |
MC04778673 |
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| PMOID |
PMO:00069477 |
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| prefixIRI |
pmo:PMO_00069477 |
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| prefLabel |
Aging |
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| Synonym |
"ageing" EXACT [] |
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| Tree Number |
T10.1.7.21 |
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| subClassOf |