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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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| Preferred Name | Insulin Secretion | |
| Synonyms |
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| Definitions |
"The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00066331 |
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| Database_Cross_Reference |
GO:0030073
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| Definition |
"The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732]
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| Gene Annotation |
LEP(UniProtKB:P41159) ILDR2(UniProtKB:Q71H61) SMAD2(UniProtKB:Q15796) FFAR1(UniProtKB:O14842) ACVR2B(UniProtKB:Q13705) CYB5R4(UniProtKB:Q7L1T6) PARK7(UniProtKB:Q99497) MC4R(UniProtKB:P32245) CPLX1(UniProtKB:O14810) GAL(UniProtKB:P22466) HNF1A(UniProtKB:P20823) HNF1B(UniProtKB:P35680) FKBP1B(UniProtKB:P68106) ADCYAP1(UniProtKB:P18509) CAMK2G(UniProtKB:Q13555) MYO5A(UniProtKB:Q9Y4I1) NEUROD1(UniProtKB:Q13562) STXBP3(UniProtKB:O00186) IL1RN(UniProtKB:P18510) PTPRN(UniProtKB:Q16849) PCLO(UniProtKB:Q9Y6V0) VGF(UniProtKB:O15240) FAM3B(UniProtKB:P58499) STX1A(UniProtKB:Q16623) MAFA(UniProtKB:Q8NHW3) PDX1(UniProtKB:P52945) CPLX3(UniProtKB:Q8WVH0) SLC30A8(UniProtKB:Q8IWU4) RIMS2(UniProtKB:Q9UQ26) SNX19(UniProtKB:Q92543) ANXA1(UniProtKB:P04083) GPR119(UniProtKB:Q8TDV5) RAPGEF4(UniProtKB:Q8WZA2)
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| label |
Insulin Secretion
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| MCID |
MC04805676
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| PMOID |
PMO:00066331
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| prefixIRI |
pmo:PMO_00066331
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| prefLabel |
Insulin Secretion
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| Tree Number |
T10.1.1.8.3.27.42.11.3.19 T10.1.26.3.30.5.2.4.17 T10.1.1.8.2.1.5.19 T10.1.1.8.3.12.7.2.17 T10.1.1.8.3.12.6.4.19 T10.1.1.8.3.3.40.23.2.5.19 T10.1.1.8.3.27.42.2.5.19 T10.1.1.2.3.1.1.5.19 T10.1.1.8.3.3.40.23.11.2.17 T10.1.29.24.4.19 T10.1.1.8.3.34.2.4.17 T10.1.1.8.3.12.6.11.4.4.17 T10.1.29.24.11.4.4.17 T10.1.1.8.3.12.7.3.19 T10.1.1.8.3.27.42.11.2.17 T10.1.1.8.3.3.40.23.11.3.19
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