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PMO Precision Medicine Ontology
Last uploaded:
December 16, 2020
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| Preferred Name | Platelet Activation | |
| Synonyms |
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| Definitions |
"A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug." [http://www.graylab.ac.uk/omd/] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00062898 |
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| Database_Cross_Reference |
GO:0030168
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| Definition |
"A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug." [http://www.graylab.ac.uk/omd/]
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| Gene Annotation |
LCP2(UniProtKB:Q13094) F2RL3(UniProtKB:Q96RI0) ADAMTS13(UniProtKB:Q76LX8) GNA12(UniProtKB:Q03113) GP6(UniProtKB:Q9HCN6) MERTK(UniProtKB:Q12866) GNAQ(UniProtKB:P50148) ARRB1(UniProtKB:P49407) DGKZ(UniProtKB:Q13574) ENTPD2(UniProtKB:Q9Y5L3) GNA14(UniProtKB:O95837) PRKCG(UniProtKB:P05129) F2(UniProtKB:P00734) DGKB(UniProtKB:Q9Y6T7) DGKK(UniProtKB:Q5KSL6) PRKCQ(UniProtKB:Q04759) GP5(UniProtKB:P40197) TRPC6(UniProtKB:Q9Y210) ITPR1(UniProtKB:Q14643) YWHAZ(UniProtKB:P63104) PIK3R6(UniProtKB:Q5UE93) PDPK1(UniProtKB:O15530) PRKCB(UniProtKB:P05771) COL3A1(UniProtKB:P02461) PF4(UniProtKB:P02776) ADRA2C(UniProtKB:P18825) GNA13(UniProtKB:Q14344) IL6(UniProtKB:P05231) P2RY1(UniProtKB:P47900) ITGB3(UniProtKB:P05106) PDPN(UniProtKB:Q86YL7) MPIG6B(UniProtKB:O95866) CD40LG(UniProtKB:P29965) ADRA2A(UniProtKB:P08913) PIK3CG(UniProtKB:P48736) DGKH(UniProtKB:Q86XP1) P2RX1(UniProtKB:P51575) TYRO3(UniProtKB:Q06418) VAV2(UniProtKB:P52735) FYN(UniProtKB:P06241) VAV3(UniProtKB:Q9UKW4) F2RL2(UniProtKB:O00254) C1GALT1C1(UniProtKB:Q96EU7) COL1A2(UniProtKB:P08123) PRKCA(UniProtKB:P17252) GNA11(UniProtKB:P29992) FZD6(UniProtKB:O60353) MAPK3(UniProtKB:P27361) HRG(UniProtKB:P04196) PRKCE(UniProtKB:Q02156) FCER1G(UniProtKB:P30273) ACTN1(UniProtKB:P12814) DGKE(UniProtKB:P52429) SRF(UniProtKB:P11831) COL1A1(UniProtKB:P02452) DGKI(UniProtKB:O75912) PRKCH(UniProtKB:P24723) PF4V1(UniProtKB:P10720) TREML1(UniProtKB:Q86YW5) PLSCR1(UniProtKB:O15162) PIK3R1(UniProtKB:P27986) PRKCD(UniProtKB:Q05655) SYK(UniProtKB:P43405) DGKA(UniProtKB:P23743) PLCG2(UniProtKB:P16885) AXL(UniProtKB:P30530) PTPN6(UniProtKB:P29350) LCK(UniProtKB:P06239) ADRA2B(UniProtKB:P18089) RAF1(UniProtKB:P04049) VAV1(UniProtKB:P15498) ARRB2(UniProtKB:P32121) FLNA(UniProtKB:P21333) TRPC3(UniProtKB:Q13507) PIK3R5(UniProtKB:Q8WYR1) TRPC7(UniProtKB:Q9HCX4) DGKG(UniProtKB:P49619) DGKD(UniProtKB:Q16760) BLOC1S3(UniProtKB:Q6QNY0) PIK3CB(UniProtKB:P42338) GNB1(UniProtKB:P62873) GAS6(UniProtKB:Q14393) CD40(UniProtKB:P25942) GNA15(UniProtKB:P30679) SAA1(UniProtKB:P0DJI8) GP9(UniProtKB:P14770) PIK3CA(UniProtKB:P42336) ITPR2(UniProtKB:Q14571) GP1BA(UniProtKB:P07359) ITPR3(UniProtKB:Q14573) CLEC1B(UniProtKB:Q9P126) VWF(UniProtKB:P04275) GNG2(UniProtKB:P59768) GP1BB(UniProtKB:P13224) LYN(UniProtKB:P07948) PTPN11(UniProtKB:Q06124) F2R(UniProtKB:P25116) CD9(UniProtKB:P21926) F8(UniProtKB:P00451) RAP2B(UniProtKB:P61225) MAPK1(UniProtKB:P28482) SRC(UniProtKB:P12931) DGKQ(UniProtKB:P52824)
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| label |
Platelet Activation
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| MCID |
MC04774444
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| PMOID |
PMO:00062898
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| prefixIRI |
pmo:PMO_00062898
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| prefLabel |
Platelet Activation
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| Synonym |
"blood coagulation, platelet activation" EXACT [GOC:add, GOC:pde]
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| Tree Number |
T10.1.29.27.3
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| subClassOf |
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