PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Adaptive Immune Response
Synonyms
Definitions

"An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149]

ID

http://www.phoc.org.cn/pmo/class/PMO_00055867

Database_Cross_Reference

GO:0002250

Definition

"An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149]

Gene Annotation

IL2(UniProtKB:P60568)

TRBJ2-1(UniProtKB:A0A0A0MTA7)

KLRK1(UniProtKB:P26718)

TRAV35(UniProtKB:P0DPF4)

IGLV1-36(UniProtKB:A0A0B4J1U3)

LILRB5(UniProtKB:O75023)

CD1B(UniProtKB:P29016)

SLAMF1(UniProtKB:Q13291)

ERAP2(UniProtKB:Q6P179)

IFNE(UniProtKB:Q86WN2)

TRBV6-3(UniProtKB:P0DPF7)

TRBV6-2(UniProtKB:A0A0J9YXY3)

TRAV6(UniProtKB:A0A075B6T7)

TRAV4(UniProtKB:A0A0B4J268)

PAG1(UniProtKB:Q9NWQ8)

TRAV29DV5(UniProtKB:P04437)

TRAV34(UniProtKB:A0A0B4J273)

IFNA6(UniProtKB:P05013)

TRBV5-1(UniProtKB:A0A578)

IFNG(UniProtKB:P01579)

TRBV11-1(UniProtKB:A0A0K0K1C0)

TRAV16(UniProtKB:A0A0A6YYK6)

IGLV8-61(UniProtKB:A0A075B6I0)

IGKV1-13(UniProtKB:P0DP09)

TRGJ1(UniProtKB:A0A075B6S0)

ZNF683(UniProtKB:Q8IZ20)

TEC(UniProtKB:P42680)

TXK(UniProtKB:P42681)

TRBV11-3(UniProtKB:A0A5A6)

ITK(UniProtKB:Q08881)

RNF125(UniProtKB:Q96EQ8)

BTK(UniProtKB:Q06187)

TRDV2(UniProtKB:A0JD36)

TRBV24-1(UniProtKB:A0A075B6N3)

TNFRSF17(UniProtKB:Q02223)

TRBV2(UniProtKB:A0A1B0GX68)

LILRB1(UniProtKB:Q8NHL6)

CD86(UniProtKB:P42081)

LAX1(UniProtKB:Q8IWV1)

FGB(UniProtKB:P02675)

TRAV25(UniProtKB:A0A0B4J276)

IGLV4-3(UniProtKB:A0A075B6K6)

IGKV3D-15(UniProtKB:A0A087WSY6)

TRGV9(UniProtKB:Q99603)

TRAV26-2(UniProtKB:A0A0B4J265)

CD46(UniProtKB:P15529)

TRBD1(UniProtKB:P0DPI4)

IGKV1-9(UniProtKB:A0A0C4DH69)

TNFRSF14(UniProtKB:Q92956)

CAMK4(UniProtKB:Q16566)

TRBJ1-1(UniProtKB:A0A0J9YXA8)

IGLV4-69(UniProtKB:A0A075B6H9)

IGLJ1(UniProtKB:A0A0A0MT76)

LAT(UniProtKB:O43561)

LILRB3(UniProtKB:O75022)

CD4(UniProtKB:P01730)

IGKJ1(UniProtKB:A0A0A0MT89)

TRAJ42(UniProtKB:A0A075B6Y9)

TRAV2(UniProtKB:A0A0B4J234)

TRAV5(UniProtKB:A0A0B4J249)

PRKCB(UniProtKB:P05771)

TRPM4(UniProtKB:Q8TD43)

SLAMF7(UniProtKB:Q9NQ25)

TRAV8-4(UniProtKB:P01737)

TFEB(UniProtKB:P19484)

TRAV24(UniProtKB:A0A0B4J272)

DCLRE1C(UniProtKB:Q96SD1)

TRAV18(UniProtKB:A0A075B6X5)

HAVCR2(UniProtKB:Q8TDQ0)

TRAV8-6(UniProtKB:A0A0B4J262)

IFNA7(UniProtKB:P01567)

IFNA4(UniProtKB:P05014)

IFNW1(UniProtKB:P05000)

IGKV3D-11(UniProtKB:A0A0A0MRZ8)

CD1A(UniProtKB:P06126)

IGKV1D-13(UniProtKB:A0A0B4J2D9)

TRGV8(UniProtKB:A0A0C4DH27)

GPR183(UniProtKB:P32249)

OTUB1(UniProtKB:Q96FW1)

TRBV27(UniProtKB:A0A0K0K1C4)

TRGV5(UniProtKB:A0A0B4J1U4)

TRAV26-1(UniProtKB:A0A087WT03)

TRAV1-1(UniProtKB:A0A0B4J248)

CD1E(UniProtKB:P15812)

IGHM(UniProtKB:P01871)

TRAV38-1(UniProtKB:A0A0B4J264)

TRAV9-1(UniProtKB:A0A075B6T8)

JAK2(UniProtKB:O60674)

CLEC4A(UniProtKB:Q9UMR7)

BTN3A1(UniProtKB:O00481)

IGKV6-21(UniProtKB:A0A0C4DH24)

PDCD1(UniProtKB:Q15116)

CD3G(UniProtKB:P09693)

VTCN1(UniProtKB:Q7Z7D3)

TRBJ1-3(UniProtKB:A0A0J9YWP8)

LAMP3(UniProtKB:Q9UQV4)

CD209(UniProtKB:Q9NNX6)

CD79A(UniProtKB:P11912)

BTLA(UniProtKB:Q7Z6A9)

TRBV18(UniProtKB:A0A087X0M5)

TRAV8-3(UniProtKB:A0A0A6YYJ7)

TNFRSF13C(UniProtKB:Q96RJ3)

TNFRSF21(UniProtKB:O75509)

PRDM1(UniProtKB:O75626)

IGKV1-6(UniProtKB:A0A0C4DH72)

JAM3(UniProtKB:Q9BX67)

TRBV7-9(UniProtKB:P04435)

PIK3CG(UniProtKB:P48736)

TRAV40(UniProtKB:A0A0B4J280)

HLA-DPA1(UniProtKB:P20036)

TRAV12-3(UniProtKB:A0A0B4J271)

TRAV17(UniProtKB:A0A0B4J275)

TRBV13(UniProtKB:A0A0A6YYD4)

LILRB4(UniProtKB:Q8NHJ6)

TRAV8-2(UniProtKB:A0A0B4J237)

TRAV8-1(UniProtKB:A0A0A6YYK1)

CD247(UniProtKB:P20963)

TRDJ1(UniProtKB:A0A075B706)

IGLV5-37(UniProtKB:A0A075B6J1)

ERAP1(UniProtKB:Q9NZ08)

FYN(UniProtKB:P06241)

IGLV3-9(UniProtKB:A0A075B6K5)

IFNA1(UniProtKB:P01562)

TRBV29-1(UniProtKB:A0A5B7)

TRAV20(UniProtKB:A0A0B4J274)

IGKV1-27(UniProtKB:A0A075B6S5)

IGLV10-54(UniProtKB:A0A075B6I4)

CD3D(UniProtKB:P04234)

CLEC6A(UniProtKB:Q6EIG7)

HLA-DRB1(UniProtKB:P01911)

FCGR1B(UniProtKB:Q92637)

IFNA21(UniProtKB:P01568)

IFNA2(UniProtKB:P01563)

TRAC(UniProtKB:P01848)

TAP2(UniProtKB:Q03519)

IFNA16(UniProtKB:P05015)

IGHJ1(UniProtKB:A0A0C4DH62)

FBXO38(UniProtKB:Q6PIJ6)

TFE3(UniProtKB:P19532)

CD3E(UniProtKB:P07766)

CD1C(UniProtKB:P29017)

TRAV36DV7(UniProtKB:A0A075B6V5)

IGKV2D-26(UniProtKB:A0A0A0MRZ7)

HMHB1(UniProtKB:O97980)

IFNB1(UniProtKB:P01574)

TRAV3(UniProtKB:A0A0B4J244)

IGLV5-45(UniProtKB:A0A087WSX0)

TRBV9(UniProtKB:A0A0B4J1U6)

JAK3(UniProtKB:P52333)

IGKV1D-17(UniProtKB:A0A075B6S4)

LAIR1(UniProtKB:Q6GTX8)

TAP1(UniProtKB:Q03518)

IGLV5-39(UniProtKB:A0A0G2JS06)

IGLV3-10(UniProtKB:A0A075B6K4)

CLEC10A(UniProtKB:Q8IUN9)

BMX(UniProtKB:P51813)

TRBV7-7(UniProtKB:A0A0K0K1E9)

RNF19B(UniProtKB:Q6ZMZ0)

SH2D1A(UniProtKB:O60880)

TRBV12-3(UniProtKB:P01733)

HLA-DPB1(UniProtKB:P04440)

PRKD2(UniProtKB:Q9BZL6)

IGKV1D-8(UniProtKB:A0A087WSZ0)

MCOLN1(UniProtKB:Q9GZU1)

SH2D1B(UniProtKB:O14796)

PIK3CD(UniProtKB:O00329)

TRAJ3(UniProtKB:A0A075B6Y3)

HLA-DRB5(UniProtKB:Q30154)

CD79B(UniProtKB:P40259)

IGLV4-60(UniProtKB:A0A075B6I1)

IGKV6D-21(UniProtKB:A0A0A0MT36)

TRBV4-3(UniProtKB:A0A589)

TRAV39(UniProtKB:A0A0B4J263)

IGKV3D-7(UniProtKB:A0A0C4DH55)

TRAV14DV4(UniProtKB:A0A0A6YYC5)

ICOSLG(UniProtKB:O75144)

TRBV6-5(UniProtKB:A0A0K0K1A5)

TRGV2(UniProtKB:A0A075B6R0)

TRAV21(UniProtKB:A0A0B4J279)

ORAI1(UniProtKB:Q96D31)

TRBV14(UniProtKB:A0A5B0)

TRBV6-8(UniProtKB:A0A0A6YYG3)

FCRL4(UniProtKB:Q96PJ5)

TRBV12-5(UniProtKB:A0A1B0GX78)

IFNA8(UniProtKB:P32881)

TRAV13-1(UniProtKB:A0A0B4J241)

TRBV6-6(UniProtKB:A0A0A6YYG2)

CD6(UniProtKB:P30203)

IGKV1D-43(UniProtKB:A0A0B4J1Z2)

TRBV6-9(UniProtKB:A0A0J9YX75)

TRAT1(UniProtKB:Q6PIZ9)

SYK(UniProtKB:P43405)

TRBV5-6(UniProtKB:A0A599)

CD8B(UniProtKB:P10966)

TRBV28(UniProtKB:A0A5B6)

CTSH(UniProtKB:P09668)

TSC1(UniProtKB:Q92574)

HLA-DQA2(UniProtKB:P01906)

MARCH8(UniProtKB:Q5T0T0)

ARG2(UniProtKB:P78540)

FCAMR(UniProtKB:Q8WWV6)

HLA-DMB(UniProtKB:P28068)

TRBV4-2(UniProtKB:A0A539)

TRGV4(UniProtKB:A0A0C4DH28)

TRAV13-2(UniProtKB:A0A0B4J235)

TRBJ1-6(UniProtKB:A0A0J9YWX3)

HLA-DRB3(UniProtKB:P79483)

ADGRE1(UniProtKB:Q14246)

TRAV12-1(UniProtKB:A0A0B4J245)

SIGLEC10(UniProtKB:Q96LC7)

TRBV20-1(UniProtKB:A0A075B6N2)

EOMES(UniProtKB:O95936)

PDCD1LG2(UniProtKB:Q9BQ51)

TRBV19(UniProtKB:A0A075B6N1)

LIME1(UniProtKB:Q9H400)

TRBV5-8(UniProtKB:A0A5A2)

ALCAM(UniProtKB:Q13740)

TNFSF18(UniProtKB:Q9UNG2)

HLA-DOA(UniProtKB:P06340)

IGLV5-52(UniProtKB:A0A0A0MRZ9)

PTK2B(UniProtKB:Q14289)

THEMIS(UniProtKB:Q8N1K5)

IGKV2-40(UniProtKB:A0A087WW87)

IGLV7-46(UniProtKB:A0A075B6I9)

TRBV5-5(UniProtKB:A0A597)

TRAV1-2(UniProtKB:A0A0B4J238)

TRBV6-1(UniProtKB:A0A0K0K1D8)

IFNA14(UniProtKB:P01570)

SIT1(UniProtKB:Q9Y3P8)

TRGC1(UniProtKB:P0CF51)

OTUD7B(UniProtKB:Q6GQQ9)

TRBV12-4(UniProtKB:A0A0B4J2E0)

CRACR2A(UniProtKB:Q9BSW2)

HLA-DQA1(UniProtKB:P01909)

LILRA3(UniProtKB:Q8N6C8)

IGLV3-16(UniProtKB:A0A075B6K0)

TRBV3-1(UniProtKB:A0A576)

TNFRSF13B(UniProtKB:O14836)

TRAV27(UniProtKB:A0A087WT01)

CD84(UniProtKB:Q9UIB8)

IGLV3-22(UniProtKB:A0A075B6J6)

TRBV7-4(UniProtKB:A0A1B0GX95)

HLA-DQB2(UniProtKB:P05538)

TRBV10-1(UniProtKB:A0A0K0K1A3)

TRAV41(UniProtKB:A0A0B4J266)

MCOLN2(UniProtKB:Q8IZK6)

TRAV30(UniProtKB:A0A087WSZ9)

TRAV9-2(UniProtKB:A0A087WT02)

HLA-DRA(UniProtKB:P01903)

RAG1(UniProtKB:P15918)

CD244(UniProtKB:Q9BZW8)

TRDD1(UniProtKB:P0DPR3)

ARG1(UniProtKB:P05089)

UNC93B1(UniProtKB:Q9H1C4)

LAG3(UniProtKB:P18627)

TNFRSF11A(UniProtKB:Q9Y6Q6)

TRAV10(UniProtKB:A0A0B4J240)

HLA-DMA(UniProtKB:P28067)

IGKV2-24(UniProtKB:A0A0C4DH68)

IGHD1-1(UniProtKB:P0DOY5)

TRBV5-4(UniProtKB:A0A0C4DH59)

RIPK2(UniProtKB:O43353)

CD7(UniProtKB:P09564)

TARM1(UniProtKB:B6A8C7)

TRAV22(UniProtKB:A0A0B4J277)

BCL10(UniProtKB:O95999)

CTSS(UniProtKB:P25774)

IGKV1-8(UniProtKB:A0A0C4DH67)

TRBV7-8(UniProtKB:A0A1B0GX51)

BTNL8(UniProtKB:Q6UX41)

NLRP10(UniProtKB:Q86W26)

PRR7(UniProtKB:Q8TB68)

TRBV10-2(UniProtKB:A0A0K0K1G8)

TRBV10-3(UniProtKB:A0A0K0K1G6)

TRDV3(UniProtKB:A0JD37)

SKAP1(UniProtKB:Q86WV1)

TRAV38-2DV8(UniProtKB:A0JD32)

TRAV12-2(UniProtKB:A0A075B6T6)

LILRB2(UniProtKB:Q8N423)

JCHAIN(UniProtKB:P01591)

CLEC4D(UniProtKB:Q8WXI8)

CLEC4C(UniProtKB:Q8WTT0)

TRBV7-2(UniProtKB:A0A1B0GXF2)

IFNA5(UniProtKB:P01569)

TRBV25-1(UniProtKB:A0A075B6N4)

IGLV3-12(UniProtKB:A0A075B6K2)

LYN(UniProtKB:P07948)

TRBV30(UniProtKB:A0A0K0K1B3)

ZAP70(UniProtKB:P43403)

LILRA1(UniProtKB:O75019)

TRBJ1-4(UniProtKB:A0A0J9YXG5)

TRGC2(UniProtKB:P03986)

C17orf99(UniProtKB:Q6UX52)

IGKV2D-29(UniProtKB:A0A075B6S2)

IFNA10(UniProtKB:P01566)

IFNK(UniProtKB:Q9P0W0)

TRBV7-6(UniProtKB:A0A1B0GX31)

TRDV1(UniProtKB:A0A1B0GX56)

TRBV11-2(UniProtKB:A0A584)

DBNL(UniProtKB:Q9UJU6)

FGL1(UniProtKB:Q08830)

TRGV3(UniProtKB:P03979)

CTLA4(UniProtKB:P16410)

CLEC4M(UniProtKB:Q9H2X3)

IGLV9-49(UniProtKB:A0A0B4J1Y8)

HLA-DOB(UniProtKB:P13765)

ANXA1(UniProtKB:P04083)

HLA-DRB4(UniProtKB:P13762)

HLA-E(UniProtKB:P13747)

TRAV19(UniProtKB:A0A0A6YYK7)

CTSL(UniProtKB:P07711)

CSK(UniProtKB:P41240)

TRAV23DV6(UniProtKB:A0A075B6W5)

FGA(UniProtKB:P02671)

NEDD4(UniProtKB:P46934)

CD274(UniProtKB:Q9NZQ7)

EIF2AK4(UniProtKB:Q9P2K8)

LILRA6(UniProtKB:Q6PI73)

TRBV4-1(UniProtKB:A0A577)

TRBJ2-7(UniProtKB:A0A0A0MT78)

LAT2(UniProtKB:Q9GZY6)

CD160(UniProtKB:O95971)

TRBV6-4(UniProtKB:A0A1B0GX49)

TRBV16(UniProtKB:A0A087WV62)

TRBJ1-5(UniProtKB:A0A0J9YXM7)

IFNA17(UniProtKB:P01571)

IGLV2-18(UniProtKB:A0A075B6J9)

CD8B2(UniProtKB:A6NJW9)

TRAV7(UniProtKB:A0A075B6U4)

label

Adaptive Immune Response

MCID

MC04802917

PMOID

PMO:00055867

prefixIRI

pmo:PMO_00055867

prefLabel

Adaptive Immune Response

Synonym

"immune memory response" EXACT [GOC:add]

"acquired immune response" EXACT [ISBN:068340007X]

Tree Number

T10.1.28.5.6

T10.1.13.6.6

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00055866

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0002250 CL LOOM
http://purl.org/obo/owl/GO#GO_0002250 BIOMODELS LOOM
http://purl.obolibrary.org/obo/GO_0002250 IDO LOOM
http://purl.obolibrary.org/obo/GO_0002250 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0002250 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0002250 PDRO LOOM
http://purl.obolibrary.org/obo/GO_0002250 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0002250 CLO LOOM
http://purl.obolibrary.org/obo/GO_0002250 OBI LOOM
http://purl.obolibrary.org/obo/GO_0002250 PLANP LOOM
http://purl.obolibrary.org/obo/GO_0002250 GCBO LOOM
http://purl.obolibrary.org/obo/GO_0002250 FOVT LOOM
http://purl.obolibrary.org/obo/GO_0002250 HOIP LOOM
http://purl.obolibrary.org/obo/GO_0002250 ONE LOOM
http://purl.obolibrary.org/obo/GO_0002250 LIFO LOOM
http://purl.obolibrary.org/obo/GO_0002250 EGO LOOM
http://purl.obolibrary.org/obo/GO_0002250 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0002250 COVID-19 LOOM
http://purl.obolibrary.org/obo/GO_0002250 PCL LOOM
http://purl.obolibrary.org/obo/GO_0002250 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0002250 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0002250 BERO LOOM
http://purl.obolibrary.org/obo/GO_0002250 HHEAR LOOM
http://purl.obolibrary.org/obo/GO_0002250 TXPO LOOM
http://purl.obolibrary.org/obo/GO_0002250 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0002250 OBI_IEE LOOM
http://purl.obolibrary.org/obo/GO_0002250 FTC LOOM
http://purl.obolibrary.org/obo/GO_0002250 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0002250 KTAO LOOM
http://purl.obolibrary.org/obo/GO_0002250 VIDO LOOM
http://purl.obolibrary.org/obo/GO_0002250 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0002250 IDOMAL LOOM
http://purl.obolibrary.org/obo/GO_0002250 MAXO LOOM
http://purl.obolibrary.org/obo/GO_0002250 IDO-COVID-19 LOOM
http://purl.obolibrary.org/obo/GO_0002250 GO LOOM
http://purl.obolibrary.org/obo/GO_0002250 IDODEN LOOM
http://purl.obolibrary.org/obo/GO_0002250 VO LOOM
http://purl.obolibrary.org/obo/GO_0002250 OBA LOOM
http://id.nlm.nih.gov/mesh/D056704 MDM LOOM
http://www.semanticweb.org/ontologies/2010/5/22/Ontology1277229984000.owl#HPI:0000157 HPIO LOOM
http://scai.fraunhofer.de/MSOntology#Adaptive_immune_response MSO LOOM