PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Trans-Golgi Network
Synonyms
Definitions

"The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination." [GOC:vw, ISBN:0815316194]

ID

http://www.phoc.org.cn/pmo/class/PMO_00054486

Database_Cross_Reference

GO:0005802

Definition

"The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination." [GOC:vw, ISBN:0815316194]

Gene Annotation

NUCB1(UniProtKB:Q02818)

STX8(UniProtKB:Q9UNK0)

PIFO(UniProtKB:Q8TCI5)

PQLC1(UniProtKB:Q8N2U9)

ATG9A(UniProtKB:Q7Z3C6)

ATP11A(UniProtKB:P98196)

CLTCL1(UniProtKB:P53675)

TRAPPC6B(UniProtKB:Q86SZ2)

BIRC6(UniProtKB:Q9NR09)

PHETA2(UniProtKB:Q6ICB4)

POSTN(UniProtKB:Q15063)

AP4B1(UniProtKB:Q9Y6B7)

RAB32(UniProtKB:Q13637)

SYT17(UniProtKB:Q9BSW7)

OPTN(UniProtKB:Q96CV9)

MARCH4(UniProtKB:Q9P2E8)

E9PAM4(UniProtKB:E9PAM4)

CDH1(UniProtKB:P12830)

CHST6(UniProtKB:Q9GZX3)

RAC1(UniProtKB:P63000)

BECN1(UniProtKB:Q14457)

ATP11C(UniProtKB:Q8NB49)

LRRK2(UniProtKB:Q5S007)

GBF1(UniProtKB:Q92538)

DENND5A(UniProtKB:Q6IQ26)

GRN(UniProtKB:P28799)

KIAA1324(UniProtKB:Q6UXG2)

SLC24A5(UniProtKB:Q71RS6)

PCSK1N(UniProtKB:Q9UHG2)

CLVS1(UniProtKB:Q8IUQ0)

SLC10A7(UniProtKB:Q0GE19)

ECPAS(UniProtKB:Q5VYK3)

CNST(UniProtKB:Q6PJW8)

STX6(UniProtKB:O43752)

GOLPH3L(UniProtKB:Q9H4A5)

YIPF1(UniProtKB:Q9Y548)

TRAPPC9(UniProtKB:Q96Q05)

CHST4(UniProtKB:Q8NCG5)

ATP11B(UniProtKB:Q9Y2G3)

FAM91A1(UniProtKB:Q658Y4)

SORL1(UniProtKB:Q92673)

GOLGA4(UniProtKB:Q13439)

DOP1B(UniProtKB:Q9Y3R5)

GOLGA1(UniProtKB:Q92805)

ATP7B(UniProtKB:P35670)

WDR11(UniProtKB:Q9BZH6)

RAB13(UniProtKB:P51153)

ADAM10(UniProtKB:O14672)

RAB10(UniProtKB:P61026)

DOP1A(UniProtKB:Q5JWR5)

ARFGEF1(UniProtKB:Q9Y6D6)

FURIN(UniProtKB:P09958)

ARFGAP2(UniProtKB:Q8N6H7)

STX16(UniProtKB:O14662)

IGF2R(UniProtKB:P11717)

TMEM230(UniProtKB:Q96A57)

PCSK4(UniProtKB:Q6UW60)

MARCH9(UniProtKB:Q86YJ5)

SLC9A7(UniProtKB:Q96T83)

PCSK7(UniProtKB:Q16549)

DNM2(UniProtKB:P50570)

GGA2(UniProtKB:Q9UJY4)

ARAP1(UniProtKB:Q96P48)

PI4K2B(UniProtKB:G5E9Z4)

ARL5A(UniProtKB:Q9Y689)

VPS54(UniProtKB:Q9P1Q0)

AZIN2(UniProtKB:Q96A70)

TBC1D23(UniProtKB:Q9NUY8)

RAB14(UniProtKB:P61106)

INPP5K(UniProtKB:Q9BT40)

RAB30(UniProtKB:Q15771)

CBY1(UniProtKB:Q9Y3M2)

YIPF2(UniProtKB:Q9BWQ6)

ARFGEF2(UniProtKB:Q9Y6D5)

ATXN2(UniProtKB:Q99700)

MME(UniProtKB:P08473)

ARL5C(UniProtKB:A6NH57)

VAMP7(UniProtKB:P51809)

RELCH(UniProtKB:Q9P260)

RAB11A(UniProtKB:P62491)

BACE2(UniProtKB:Q9Y5Z0)

PCSK5(UniProtKB:Q92824)

CHST3(UniProtKB:Q7LGC8)

RAB21(UniProtKB:Q9UL25)

CHST1(UniProtKB:O43916)

WIPI1(UniProtKB:Q5MNZ9)

TRAPPC6A(UniProtKB:O75865)

RAB6A(UniProtKB:P20340)

RAB38(UniProtKB:P57729)

CORO7(UniProtKB:P57737)

SYS1-DBNDD2(UniProtKB:H3BUS1)

CHID1(UniProtKB:Q9BWS9)

VAMP2(UniProtKB:P63027)

CLIP3(UniProtKB:Q96DZ5)

ATP9A(UniProtKB:O75110)

RAB29(UniProtKB:O14966)

VPS51(UniProtKB:Q9UID3)

KLHL20(UniProtKB:Q9Y2M5)

BACE1(UniProtKB:P56817)

BICD1(UniProtKB:Q96G01)

EIPR1(UniProtKB:Q53HC9)

SYS1(UniProtKB:Q8N2H4)

PRKD1(UniProtKB:Q15139)

GOLPH3(UniProtKB:Q9H4A6)

MICALL1(UniProtKB:Q8N3F8)

LAP3(UniProtKB:P28838)

ARL5B(UniProtKB:Q96KC2)

TGFBI(UniProtKB:Q15582)

OSBP(UniProtKB:P22059)

WLS(UniProtKB:Q5T9L3)

PLOD3(UniProtKB:O60568)

GCC2(UniProtKB:Q8IWJ2)

CLN3(UniProtKB:Q13286)

SMPD4(UniProtKB:Q9NXE4)

CA4(UniProtKB:P22748)

TJAP1(UniProtKB:Q5JTD0)

SCOC(UniProtKB:Q9UIL1)

ARFRP1(UniProtKB:Q13795)

CHST5(UniProtKB:Q9GZS9)

CLASP2(UniProtKB:O75122)

RGS20(UniProtKB:O76081)

M6PR(UniProtKB:P20645)

TAS2R16(UniProtKB:Q9NYV7)

CLVS2(UniProtKB:Q5SYC1)

RAB12(UniProtKB:Q6IQ22)

PI4K2B(UniProtKB:Q8TCG2)

YIPF6(UniProtKB:Q96EC8)

MLANA(UniProtKB:Q16655)

ATP7A(UniProtKB:Q04656)

CHAC1(UniProtKB:Q9BUX1)

GGA3(UniProtKB:Q9NZ52)

SNX9(UniProtKB:Q9Y5X1)

ARF1(UniProtKB:P84077)

OCRL(UniProtKB:Q01968)

ATP9B(UniProtKB:O43861)

PLEKHA8(UniProtKB:Q96JA3)

STX10(UniProtKB:O60499)

PAM(UniProtKB:P19021)

GSAP(UniProtKB:A4D1B5)

PLEKHJ1(UniProtKB:Q9NW61)

TGOLN2(UniProtKB:O43493)

PI4K2A(UniProtKB:Q9BTU6)

SNAP25(UniProtKB:P60880)

SCAMP1(UniProtKB:O15126)

DPY30(UniProtKB:Q9C005)

CLTB(UniProtKB:P09497)

MYO18A(UniProtKB:Q92614)

ARL1(UniProtKB:P40616)

CHST7(UniProtKB:Q9NS84)

GOLT1A(UniProtKB:Q6ZVE7)

ATP8A1(UniProtKB:Q9Y2Q0)

PHETA1(UniProtKB:Q8N4B1)

CHST2(UniProtKB:Q9Y4C5)

GPER1(UniProtKB:Q99527)

GBA(UniProtKB:P04062)

STX4(UniProtKB:Q12846)

C16orf70(UniProtKB:Q9BSU1)

CCDC91(UniProtKB:Q7Z6B0)

C17orf75(UniProtKB:Q9HAS0)

NMNAT2(UniProtKB:Q9BZQ4)

GCNT1(UniProtKB:Q02742)

AP4M1(UniProtKB:O00189)

RBFOX1(UniProtKB:Q9NWB1)

NBEA(UniProtKB:Q8NFP9)

ATP2C1(UniProtKB:P98194)

RAB7B(UniProtKB:Q96AH8)

ARFGAP3(UniProtKB:Q9NP61)

label

Trans-Golgi Network

MCID

MC04789413

PMOID

PMO:00054486

prefixIRI

pmo:PMO_00054486

prefLabel

Trans-Golgi Network

Synonym

"maturing face" RELATED []

"TGN" EXACT []

"Golgi trans-face" RELATED []

"Golgi trans face" RELATED []

"trans Golgi network" EXACT []

"trans face" BROAD [NIF_Subcellular:sao1039242387]

"late Golgi" RELATED [GOC:mah]

Tree Number

T10.3.7.100.7.148.11.1

T10.3.14.13.15.4.1

T10.3.7.100.34.1.11.1

T10.3.14.13.1.11.1

T10.3.7.100.34.15.4.1

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00054484

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Delete Mapping To Ontology Source
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C33802 NCIT LOOM
http://purl.org/obo/owl/GO#GO_0005802 BIOMODELS LOOM
http://uri.neuinfo.org/nif/nifstd/sao9456487 NIFSTD LOOM
http://purl.jp/bio/4/id/200906045700724980 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0020822 OMIT LOOM
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#sao9456487 NIFSUBCELL LOOM
http://www.semanticweb.org/ADMO#c21 ADMO LOOM
http://www.pepathway.org/peo/1.2#trans-Golgi_Network PE-O LOOM
http://purl.obolibrary.org/obo/MESH_D021601 BERO LOOM
http://purl.org/obo/owlapi/fma#FMA_61756 BIOMODELS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A11.284.430.214.190.875.336.850 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D021601 RH-MESH LOOM
http://purl.obolibrary.org/obo/GO_0005802 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0005802 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0005802 CCO LOOM
http://purl.obolibrary.org/obo/GO_0005802 REXO LOOM
http://purl.obolibrary.org/obo/GO_0005802 GEXO LOOM
http://purl.obolibrary.org/obo/GO_0005802 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0005802 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0005802 BERO LOOM
http://purl.obolibrary.org/obo/GO_0005802 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0005802 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0005802 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0005802 RETO LOOM
http://purl.obolibrary.org/obo/GO_0005802 GO LOOM
http://purl.obolibrary.org/obo/GO_0005802 ZP LOOM
http://purl.obolibrary.org/obo/NCIT_C33802 BERO LOOM
http://ccdb.ucsd.edu/SAO/1.2#sao9456487 SAO LOOM
http://purl.bioontology.org/ontology/MESH/D021601 MESH LOOM
http://purl.org/sig/ont/fma/fma61756 FMA LOOM