loading...| Preferred Name |
Apical Junction Complex |
|
| Synonyms |
|
|
| Definitions |
"A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." [GOC:go_curators, GOC:kmv, PMID:12525486, PMID:15196556] |
|
| ID |
http://www.phoc.org.cn/pmo/class/PMO_00051548 |
|
| Database_Cross_Reference |
GO:0043296 |
|
| Definition |
"A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." [GOC:go_curators, GOC:kmv, PMID:12525486, PMID:15196556] |
|
| Gene Annotation |
SHROOM1(UniProtKB:Q2M3G4) PARD3B(UniProtKB:Q8TEW8) CCDC85C(UniProtKB:A6NKD9) CDH1(UniProtKB:P12830) NECTIN3(UniProtKB:Q9NQS3) PARD3(UniProtKB:Q8TEW0) NECTIN4(UniProtKB:Q96NY8) SAPCD2(UniProtKB:Q86UD0) SHROOM2(UniProtKB:Q13796) SHROOM3(UniProtKB:Q8TF72) CLDN19(UniProtKB:Q8N6F1) FRMD6(UniProtKB:Q96NE9) FBF1(UniProtKB:Q8TES7) RHOA(UniProtKB:P61586) NECTIN1(UniProtKB:Q15223) SHROOM4(UniProtKB:Q9ULL8) PKN2(UniProtKB:Q16513) TJP1(UniProtKB:Q07157) |
|
| label |
Apical Junction Complex |
|
| MCID |
MC04802086 |
|
| PMOID |
PMO:00051548 |
|
| prefixIRI |
pmo:PMO_00051548 |
|
| prefLabel |
Apical Junction Complex |
|
| Synonym |
"apical cell junction complex" EXACT [GOC:mah] "apical junction" EXACT [] |
|
| Tree Number |
T10.3.1.3.9 |
|
| subClassOf |