PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Desmosome
Synonyms
Definitions

"A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181]

ID

http://www.phoc.org.cn/pmo/class/PMO_00051543

Database_Cross_Reference

GO:0030057

Definition

"A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181]

Gene Annotation

PKP3(UniProtKB:Q9Y446)

PKP1(UniProtKB:Q13835)

DSG4(UniProtKB:Q86SJ6)

UBA1(UniProtKB:P22314)

KLHL24(UniProtKB:Q6TFL4)

DSC3(UniProtKB:Q14574)

POF1B(UniProtKB:Q8WVV4)

JAM3(UniProtKB:Q9BX67)

PKP4(UniProtKB:Q99569)

DSP(UniProtKB:P15924)

PERP(UniProtKB:Q96FX8)

CDSN(UniProtKB:Q15517)

JUP(UniProtKB:P14923)

PKP2(UniProtKB:Q99959)

DSC1(UniProtKB:Q08554)

DSC2(UniProtKB:Q02487)

DSG1(UniProtKB:Q02413)

PPL(UniProtKB:O60437)

DSG2(UniProtKB:Q14126)

TCHP(UniProtKB:Q9BT92)

PNN(UniProtKB:Q9H307)

DSG3(UniProtKB:P32926)

KAZN(UniProtKB:Q674X7)

EVPL(UniProtKB:Q92817)

B4GALT1(UniProtKB:P15291)

label

Desmosome

MCID

MC04785432

PMOID

PMO:00051543

prefixIRI

pmo:PMO_00051543

prefLabel

Desmosome

Synonym

"spot desmosome" EXACT []

"macula adherens" EXACT []

Tree Number

T10.3.1.2.1

T10.3.1.3.1

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00051567

http://www.phoc.org.cn/pmo/class/PMO_00051531

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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/LNC/LP149594-6 LOINC LOOM
http://purl.obolibrary.org/obo/ECAO_0109380 ECAO LOOM
http://purl.obolibrary.org/obo/GO_0030057 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0030057 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0030057 CCONT LOOM
http://purl.obolibrary.org/obo/GO_0030057 CCO LOOM
http://purl.obolibrary.org/obo/GO_0030057 REXO LOOM
http://purl.obolibrary.org/obo/GO_0030057 GEXO LOOM
http://purl.obolibrary.org/obo/GO_0030057 EFO LOOM
http://purl.obolibrary.org/obo/GO_0030057 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0030057 COVID-19 LOOM
http://purl.obolibrary.org/obo/GO_0030057 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0030057 BERO LOOM
http://purl.obolibrary.org/obo/GO_0030057 EFO LOOM
http://purl.obolibrary.org/obo/GO_0030057 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0030057 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0030057 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0030057 RETO LOOM
http://purl.obolibrary.org/obo/GO_0030057 GO LOOM
http://purl.obolibrary.org/obo/GO_0030057 ZP LOOM
http://www.semanticweb.org/ontologies/2008/8/MultiscaleSkinPhysiologyOntology.owl#Desmosome SPO LOOM
http://purl.org/sig/ont/fma/fma67412 FMA LOOM
http://purl.obolibrary.org/obo/NCIT_C13955 BERO LOOM
http://www.projecthalo.com/aura#Desmosome AURA LOOM
http://purl.obolibrary.org/obo/XAO_0005500 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0005500 XAO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011703 OCHV LOOM
http://purl.jp/bio/4/id/200906080190037193 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/T-E0215 SNMI LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13955 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/4573009 SNOMEDCT LOOM
http://purl.org/obo/owl/GO#GO_0030057 BIOMODELS LOOM
http://purl.org/obo/owlapi/fma#FMA_67412 BIOMODELS LOOM