PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Protein Serine/threonine Kinase Activity
Synonyms
Definitions

"Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:bf]

ID

http://www.phoc.org.cn/pmo/class/PMO_00044335

Database_Cross_Reference

GO:0004674

Definition

"Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:bf]

Gene Annotation

GRK5(UniProtKB:P34947)

MTOR(UniProtKB:P42345)

MAPKAPK3(UniProtKB:Q16644)

BMPR1B(UniProtKB:O00238)

MAP4K5(UniProtKB:Q9Y4K4)

SPEG(UniProtKB:Q15772)

MAPK6(UniProtKB:Q16659)

STK4(UniProtKB:Q13043)

ULK2(UniProtKB:Q8IYT8)

VRK3(UniProtKB:Q8IV63)

SBK1(UniProtKB:Q52WX2)

ILK(UniProtKB:Q13418)

MAP2K6(UniProtKB:P52564)

CIT(UniProtKB:O14578)

MAP2K4(UniProtKB:P45985)

CDC42BPA(UniProtKB:Q5VT25)

CLK1(UniProtKB:P49759)

HIPK1(UniProtKB:Q86Z02)

TTN(UniProtKB:Q8WZ42)

MAST2(UniProtKB:Q6P0Q8)

Q9H521(UniProtKB:Q9H521)

AATK(UniProtKB:Q6ZMQ8)

TTBK1(UniProtKB:Q5TCY1)

CDKL5(UniProtKB:O76039)

BUB1(UniProtKB:O43683)

HUNK(UniProtKB:P57058)

STK10(UniProtKB:O94804)

CDK1(UniProtKB:P06493)

MAP4K1(UniProtKB:Q92918)

PLK2(UniProtKB:Q9NYY3)

PAK6(UniProtKB:Q9NQU5)

FASTK(UniProtKB:Q14296)

TRPM6(UniProtKB:Q9BX84)

ERN2(UniProtKB:Q76MJ5)

CSNK2A1(UniProtKB:P68400)

PRKCG(UniProtKB:P05129)

PIM2(UniProtKB:Q9P1W9)

NEK4(UniProtKB:P51957)

H0YJX3(UniProtKB:H0YJX3)

PLK3(UniProtKB:Q9H4B4)

TLK1(UniProtKB:Q9UKI8)

STK40(UniProtKB:Q8N2I9)

PRKCQ(UniProtKB:Q04759)

MYO3B(UniProtKB:Q8WXR4)

ERN1(UniProtKB:O75460)

LRRK1(UniProtKB:Q38SD2)

ACVR2B(UniProtKB:Q13705)

PRKACA(UniProtKB:P17612)

LRRK2(UniProtKB:Q5S007)

BRAF(UniProtKB:P15056)

MAPK13(UniProtKB:O15264)

PBK(UniProtKB:Q96KB5)

PRKDC(UniProtKB:P78527)

NEK6(UniProtKB:Q9HC98)

RIPK3(UniProtKB:Q9Y572)

MAP4K4(UniProtKB:O95819)

AURKA(UniProtKB:O14965)

SGK2(UniProtKB:Q9HBY8)

NEK3(UniProtKB:P51956)

CAB39(UniProtKB:Q9Y376)

STK11(UniProtKB:Q15831)

CSNK1E(UniProtKB:P49674)

SLK(UniProtKB:Q9H2G2)

DYRK3(UniProtKB:O43781)

PKMYT1(UniProtKB:Q99640)

PRKY(UniProtKB:O43930)

MARK3(UniProtKB:P27448)

PDPK1(UniProtKB:O15530)

PRKCB(UniProtKB:P05771)

STK31(UniProtKB:Q9BXU1)

RPS6KA5(UniProtKB:O75582)

AKT2(UniProtKB:P31751)

STK38(UniProtKB:Q15208)

MAP3K3(UniProtKB:Q99759)

TSSK3(UniProtKB:Q96PN8)

TAOK3(UniProtKB:Q9H2K8)

CSNK1G2(UniProtKB:P78368)

DAPK2(UniProtKB:Q9UIK4)

TSSK2(UniProtKB:Q96PF2)

BRSK2(UniProtKB:Q8IWQ3)

SMG1(UniProtKB:Q96Q15)

RIPK1(UniProtKB:Q13546)

CSNK2B(UniProtKB:P67870)

A0A1B0GVD9(UniProtKB:A0A1B0GVD9)

LIMK2(UniProtKB:P53671)

PDPK2P(UniProtKB:Q6A1A2)

STK3(UniProtKB:Q13188)

PASK(UniProtKB:Q96RG2)

IRAK2(UniProtKB:O43187)

MAP2K7(UniProtKB:O14733)

VRK2(UniProtKB:Q86Y07)

PRKAA2(UniProtKB:P54646)

STK19(UniProtKB:P49842)

ARAF(UniProtKB:P10398)

SIK1(UniProtKB:P57059)

DAPK1(UniProtKB:P53355)

MELK(UniProtKB:Q14680)

RSKR(UniProtKB:Q96LW2)

STK25(UniProtKB:O00506)

PIM1(UniProtKB:P11309)

LATS2(UniProtKB:Q9NRM7)

SIK1B(UniProtKB:A0A0B4J2F2)

ATR(UniProtKB:Q13535)

RIPK4(UniProtKB:P57078)

NEK8(UniProtKB:Q86SG6)

IRAK3(UniProtKB:Q9Y616)

PKN1(UniProtKB:Q16512)

NUAK2(UniProtKB:Q9H093)

HASPIN(UniProtKB:Q8TF76)

RIOK2(UniProtKB:Q9BVS4)

ADCK5(UniProtKB:Q3MIX3)

BUB1B(UniProtKB:O60566)

A0A0U1RQM0(UniProtKB:A0A0U1RQM0)

ULK4(UniProtKB:Q96C45)

MAP3K19(UniProtKB:Q56UN5)

STK38L(UniProtKB:Q9Y2H1)

PIK3CG(UniProtKB:P48736)

PRPF4B(UniProtKB:Q13523)

DAPK3(UniProtKB:O43293)

MAP4K3(UniProtKB:Q8IVH8)

NIM1K(UniProtKB:Q8IY84)

MYO3A(UniProtKB:Q8NEV4)

SRPK1(UniProtKB:Q96SB4)

BRSK1(UniProtKB:Q8TDC3)

STRADA(UniProtKB:Q7RTN6)

HIPK4(UniProtKB:Q8NE63)

PAK3(UniProtKB:O75914)

TESK1(UniProtKB:Q15569)

IKBKE(UniProtKB:Q14164)

RPS6KA3(UniProtKB:P51812)

NRBP2(UniProtKB:Q9NSY0)

MAPKAPK5(UniProtKB:Q8IW41)

TAOK1(UniProtKB:Q7L7X3)

NUAK1(UniProtKB:O60285)

CDK9(UniProtKB:P50750)

CAMK2A(UniProtKB:Q9UQM7)

CLK3(UniProtKB:P49761)

IKBKB(UniProtKB:O14920)

MAPK12(UniProtKB:P53778)

TOP1(UniProtKB:P11387)

STKLD1(UniProtKB:Q8NE28)

PRKAA1(UniProtKB:Q13131)

RPS6KA4(UniProtKB:O75676)

STK32C(UniProtKB:Q86UX6)

HIPK3(UniProtKB:Q9H422)

PRKCA(UniProtKB:P17252)

PAK5(UniProtKB:Q9P286)

MASTL(UniProtKB:Q96GX5)

MOS(UniProtKB:P00540)

TLK2(UniProtKB:Q86UE8)

SIK2(UniProtKB:Q9H0K1)

NME2(UniProtKB:P22392)

MAP2K3(UniProtKB:P46734)

UHMK1(UniProtKB:Q8TAS1)

WNK4(UniProtKB:Q96J92)

CHUK(UniProtKB:O15111)

PSKH1(UniProtKB:P11801)

DSTYK(UniProtKB:Q6XUX3)

ALPK3(UniProtKB:Q96L96)

M0QYV0(UniProtKB:M0QYV0)

PRKCE(UniProtKB:Q02156)

GSK3A(UniProtKB:P49840)

SIK3(UniProtKB:Q9Y2K2)

ACVR1B(UniProtKB:P36896)

TNK2(UniProtKB:Q07912)

TAOK2(UniProtKB:Q9UL54)

PSKH2(UniProtKB:Q96QS6)

MAP3K1(UniProtKB:Q13233)

MAK(UniProtKB:P20794)

ACVR1(UniProtKB:Q04771)

PPM1D(UniProtKB:O15297)

STK39(UniProtKB:Q9UEW8)

ANKK1(UniProtKB:Q8NFD2)

PIK3R4(UniProtKB:Q99570)

STK36(UniProtKB:Q9NRP7)

TSSK4(UniProtKB:Q6SA08)

PRKD2(UniProtKB:Q9BZL6)

PLK4(UniProtKB:O00444)

AAK1(UniProtKB:Q2M2I8)

DCLK3(UniProtKB:Q9C098)

MARK1(UniProtKB:Q9P0L2)

CDK16(UniProtKB:Q00536)

MAP3K14(UniProtKB:Q99558)

SRPK3(UniProtKB:Q9UPE1)

TESK2(UniProtKB:Q96S53)

NEK10(UniProtKB:Q6ZWH5)

FAM20C(UniProtKB:Q8IXL6)

MAP3K8(UniProtKB:P41279)

CHEK1(UniProtKB:O14757)

ACVR1C(UniProtKB:Q8NER5)

ULK3(UniProtKB:Q6PHR2)

CSNK1D(UniProtKB:P48730)

DYRK4(UniProtKB:Q9NR20)

CDK10(UniProtKB:Q15131)

CDK11B(UniProtKB:P21127)

ROCK2(UniProtKB:O75116)

MAPK4(UniProtKB:P31152)

TAF1L(UniProtKB:Q8IZX4)

STK26(UniProtKB:Q9P289)

CDC42BPB(UniProtKB:Q9Y5S2)

MAP3K4(UniProtKB:Q9Y6R4)

PRKCH(UniProtKB:P24723)

MAPK8(UniProtKB:P45983)

MAP3K7(UniProtKB:O43318)

CSNK1G1(UniProtKB:Q9HCP0)

MINK1(UniProtKB:Q8N4C8)

TTBK2(UniProtKB:Q6IQ55)

PRKCD(UniProtKB:Q05655)

SYK(UniProtKB:P43405)

PRKD1(UniProtKB:Q15139)

GAK(UniProtKB:O14976)

TP53RK(UniProtKB:Q96S44)

MAP3K10(UniProtKB:Q02779)

SQSTM1(UniProtKB:Q13501)

AKT3(UniProtKB:Q9Y243)

RPS6KA2(UniProtKB:Q15349)

TGFBR1(UniProtKB:P36897)

CPNE3(UniProtKB:O75131)

NLK(UniProtKB:Q9UBE8)

CDK11A(UniProtKB:Q9UQ88)

DCLK1(UniProtKB:O15075)

MAP3K20(UniProtKB:Q9NYL2)

CAB39L(UniProtKB:Q9H9S4)

CDK5(UniProtKB:Q00535)

OXSR1(UniProtKB:O95747)

NEK5(UniProtKB:Q6P3R8)

STK24(UniProtKB:Q9Y6E0)

TBK1(UniProtKB:Q9UHD2)

BMP2K(UniProtKB:Q9NSY1)

STK33(UniProtKB:Q9BYT3)

FAM20A(UniProtKB:Q96MK3)

RPS6KB1(UniProtKB:P23443)

RAF1(UniProtKB:P04049)

RIOK3(UniProtKB:O14730)

MLKL(UniProtKB:Q8NB16)

LMTK3(UniProtKB:Q96Q04)

TRIO(UniProtKB:O75962)

NRK(UniProtKB:Q7Z2Y5)

SNRK(UniProtKB:Q9NRH2)

PKN2(UniProtKB:Q16513)

IRAK1(UniProtKB:P51617)

MAST4(UniProtKB:O15021)

CSNK1A1(UniProtKB:P48729)

ADCK2(UniProtKB:Q7Z695)

GSK3B(UniProtKB:P49841)

KALRN(UniProtKB:O60229)

PINK1(UniProtKB:Q9BXM7)

PLK1(UniProtKB:P53350)

MAP2K5(UniProtKB:Q13163)

PAK2(UniProtKB:Q13177)

CDC7(UniProtKB:O00311)

AKT1(UniProtKB:P31749)

SRPK2(UniProtKB:P78362)

MAP3K9(UniProtKB:P80192)

EIF2AK3(UniProtKB:Q9NZJ5)

CSNK1G3(UniProtKB:Q9Y6M4)

FPGT-TNNI3K(UniProtKB:V9GXZ4)

MAP3K5(UniProtKB:Q99683)

CDK18(UniProtKB:Q07002)

PHKG2(UniProtKB:P15735)

PRKCZ(UniProtKB:Q05513)

SBK3(UniProtKB:P0C264)

WNK1(UniProtKB:Q9H4A3)

MAPK14(UniProtKB:Q16539)

CAMKK1(UniProtKB:Q8N5S9)

PDK3(UniProtKB:Q15120)

MARK4(UniProtKB:Q96L34)

WNK3(UniProtKB:Q9BYP7)

PAK4(UniProtKB:O96013)

MKNK1(UniProtKB:Q9BUB5)

CLK4(UniProtKB:Q9HAZ1)

KSR2(UniProtKB:Q6VAB6)

ATM(UniProtKB:Q13315)

HIPK2(UniProtKB:Q9H2X6)

OBSCN(UniProtKB:Q5VST9)

WNK2(UniProtKB:Q9Y3S1)

MARK2(UniProtKB:Q7KZI7)

TSSK1B(UniProtKB:Q9BXA7)

MAP3K11(UniProtKB:Q16584)

MAST3(UniProtKB:O60307)

PIK3CA(UniProtKB:P42336)

ADCK1(UniProtKB:Q86TW2)

EIF2AK2(UniProtKB:P19525)

SBK2(UniProtKB:P0C263)

CHEK2(UniProtKB:O96017)

STK32B(UniProtKB:Q9NY57)

SGK3(UniProtKB:Q96BR1)

NRBP1(UniProtKB:Q9UHY1)

CDK15(UniProtKB:Q96Q40)

LATS1(UniProtKB:O95835)

ACVR2A(UniProtKB:P27037)

BMPR1A(UniProtKB:P36894)

NEK1(UniProtKB:Q96PY6)

DCLK2(UniProtKB:Q8N568)

RIPK2(UniProtKB:O43353)

LIMK1(UniProtKB:P53667)

PDIK1L(UniProtKB:Q8N165)

MAPKAPK2(UniProtKB:P49137)

RPS6KL1(UniProtKB:Q9Y6S9)

CLK2(UniProtKB:P49760)

DYRK1B(UniProtKB:Q9Y463)

MAST1(UniProtKB:Q9Y2H9)

NEK2(UniProtKB:P51955)

CSNK1A1L(UniProtKB:Q8N752)

TTK(UniProtKB:P33981)

NEK9(UniProtKB:Q8TD19)

CDK7(UniProtKB:P50613)

MAPK11(UniProtKB:Q15759)

TRPM7(UniProtKB:Q96QT4)

RPS6KA1(UniProtKB:Q15418)

MAP2K2(UniProtKB:P36507)

MKNK2(UniProtKB:Q9HBH9)

STK17B(UniProtKB:O94768)

MAP4K2(UniProtKB:Q12851)

RPS6KB2(UniProtKB:Q9UBS0)

RPS6KC1(UniProtKB:Q96S38)

TAF1(UniProtKB:P21675)

NEK7(UniProtKB:Q8TDX7)

DYRK1A(UniProtKB:Q13627)

TNIK(UniProtKB:Q9UKE5)

CASK(UniProtKB:O14936)

BCKDK(UniProtKB:O14874)

CAMK2D(UniProtKB:Q13557)

ULK1(UniProtKB:O75385)

STK32A(UniProtKB:Q8WU08)

CSNK2A2(UniProtKB:P19784)

STK16(UniProtKB:O75716)

ROCK1(UniProtKB:Q13464)

STK17A(UniProtKB:Q9UEE5)

NEK11(UniProtKB:Q8NG66)

CDC42BPG(UniProtKB:Q6DT37)

MOK(UniProtKB:Q9UQ07)

STRADB(UniProtKB:Q9C0K7)

TNNI3K(UniProtKB:Q59H18)

MAP3K2(UniProtKB:Q9Y2U5)

ALPK2(UniProtKB:Q86TB3)

MAP3K12(UniProtKB:Q12852)

STK35(UniProtKB:Q8TDR2)

MAP2K1(UniProtKB:Q02750)

AURKB(UniProtKB:Q96GD4)

CDK2(UniProtKB:P24941)

PRKCI(UniProtKB:P41743)

PIM3(UniProtKB:Q86V86)

CDK17(UniProtKB:Q00537)

PKN3(UniProtKB:Q6P5Z2)

TSSK6(UniProtKB:Q9BXA6)

ICK(UniProtKB:Q9UPZ9)

DYRK2(UniProtKB:Q92630)

EIF2AK4(UniProtKB:Q9P2K8)

PAK1(UniProtKB:Q13153)

RIOK1(UniProtKB:Q9BRS2)

IRAK4(UniProtKB:Q9NWZ3)

MAP3K13(UniProtKB:O43283)

ACVRL1(UniProtKB:P37023)

DMPK(UniProtKB:Q09013)

ALPK1(UniProtKB:Q96QP1)

MAPK1(UniProtKB:P28482)

CSNK2A3(UniProtKB:Q8NEV1)

LMTK2(UniProtKB:Q8IWU2)

SGK1(UniProtKB:O00141)

VRK1(UniProtKB:Q99986)

BCR(UniProtKB:P11274)

label

Protein Serine/threonine Kinase Activity

MCID

MC04767422

PMOID

PMO:00044335

prefixIRI

pmo:PMO_00044335

prefLabel

Protein Serine/threonine Kinase Activity

Synonym

"protein kinase (phosphorylating) activity" NARROW [EC:2.7.11.1]

"serine(threonine) protein kinase activity" EXACT [EC:2.7.11.1]

"serine/threonine protein kinase activity" EXACT [EC:2.7.11.1]

"protein-serine kinase activity" NARROW [EC:2.7.11.1]

"threonine-specific protein kinase activity" NARROW [EC:2.7.11.1]

"serine protein kinase activity" NARROW [EC:2.7.11.1]

"protein phosphokinase activity" NARROW [EC:2.7.11.1]

"serine-specific protein kinase activity" NARROW [EC:2.7.11.1]

"protein serine kinase activity" NARROW [EC:2.7.11.1]

"serine kinase activity" NARROW [EC:2.7.11.1]

"protein serine-threonine kinase activity" EXACT [EC:2.7.11.1]

Tree Number

T10.2.6.2.53.14

T10.2.6.7.16.4.54.14

T10.2.6.7.16.9.53.14

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00044328

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