loading...| Preferred Name |
secondary cultured cell population |
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| Synonyms |
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| Definitions |
The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. A cultured cell population that is derived through one or more passages in culture. |
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| ID |
http://purl.obolibrary.org/obo/OBI_0001905 |
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| comment |
The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally. |
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| alternative term |
secondary cell culture sample |
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| definition source |
PERSON:Matthew Brush |
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| editor note |
The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture. |
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| editor preferred term |
secondary cultured cell population |
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| has curation status | ||
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| is_specified_output_of | ||
| label |
secondary cultured cell population |
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| prefixIRI |
OBI:0001905 |
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| prefLabel |
secondary cultured cell population |
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| term editor |
PERSON:Matthew Brush |
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| textual definition |
A cultured cell population that is derived through one or more passages in culture. |
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