loading...| Preferred Name | gene knock in | |
| Synonyms |
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| Definitions |
a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a "targeted" insertion. |
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| ID |
http://purl.obolibrary.org/obo/OBI_0001149 |
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| definition source |
WEB: http://en.wikipedia.org/wiki/Gene_Knock-in MO_437 gene_knock_in |
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| editor preferred term |
gene knock in |
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| has curation status | ||
| label |
gene knock in |
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| prefixIRI |
OBI:0001149 |
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| prefLabel |
gene knock in |
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| term editor |
PERSON: Chris Stoeckert, Jie Zheng |
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| textual definition |
a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a "targeted" insertion. |
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| subClassOf |