loading...| Preferred Name |
Sugammadex |
|
| Synonyms |
sugammadex |
|
| Definitions |
An octasaccharide derivative that is gamma-cyclodextrin in which all eight primary hydroxy groups are replaced by 2-(carboxyethyl)sulfanyl groups. Used (as the octasodium salt) for reversal of neuromuscular blockade induced by rocuronium and vecuronium in adults undergoing surgery. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_90953 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:26634077 PMID:26534102 PMID:26564297 PMID:26533808 PMID:26401735 Drug_Central:4233 Wikipedia:Sugammadex PMID:26449072 PMID:26437552 PMID:26437551 PMID:26418697 PMID:26750413 PMID:26750414 PMID:26394365 PMID:26472231 PMID:26748952 PMID:26684534 PMID:26597732 PMID:26409923 PMID:26351827 PMID:26505986 PMID:26271275 PMID:26508869 PMID:26322661 PMID:26437545 PMID:26673602 PMID:26485626 PMID:26747019 PMID:26558858 PMID:26685122 PMID:26398716 CAS:343306-71-8 PMID:26456087 PMID:26558864 PMID:26558863 PMID:26646837 |
|
| formula |
C72H112O48S8 |
|
| has functional parent | ||
| has role | ||
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
sugammadex |
|
| has_RxCUI |
1726988 |
|
| id |
CHEBI:90953 |
|
| in_subset | ||
| inchi |
InChI=1S/C72H112O48S8/c73-33(74)1-9-121-17-25-57-41(89)49(97)65(105-25)114-58-26(18-122-10-2-34(75)76)107-67(51(99)43(58)91)116-60-28(20-124-12-4-36(79)80)109-69(53(101)45(60)93)118-62-30(22-126-14-6-38(83)84)111-71(55(103)47(62)95)120-64-32(24-128-16-8-40(87)88)112-72(56(104)48(64)96)119-63-31(23-127-15-7-39(85)86)110-70(54(102)46(63)94)117-61-29(21-125-13-5-37(81)82)108-68(52(100)44(61)92)115-59-27(19-123-11-3-35(77)78)106-66(113-57)50(98)42(59)90/h25-32,41-72,89-104H,1-24H2,(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88)/t25-,26-,27-,28-,29-,30-,31-,32-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-/m1/s1 |
|
| inchikey |
WHRODDIHRRDWEW-VTHZAVIASA-N |
|
| is conjugate acid of | ||
| label |
sugammadex Sugammadex |
|
| mass |
2002.162 |
|
| monoisotopicmass |
2000.40887 |
|
| notation |
CHEBI:90953 |
|
| prefixIRI |
CHEBI:90953 |
|
| prefLabel |
Sugammadex |
|
| smiles |
O1[C@H](CSCCC(=O)O)[C@@H]2[C@H](O)[C@@H](O)[C@H]1O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]8[C@H](O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]9[C@H](O[C@@H]([C@@H]([C@H]9O)O)O2)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(O)=O)CSCCC(=O)O |
|
| textual definition |
An octasaccharide derivative that is gamma-cyclodextrin in which all eight primary hydroxy groups are replaced by 2-(carboxyethyl)sulfanyl groups. Used (as the octasodium salt) for reversal of neuromuscular blockade induced by rocuronium and vecuronium in adults undergoing surgery. |
|
| subClassOf |