The Prescription of Drugs Ontology

Last uploaded: September 4, 2020
Preferred Name

Carglumic acid

Synonyms

N-carbamoyl-L-glutamic acid

acidum carglumicum

carglumic acid

acide carglumique

Ureidoglutaric acid

Carbamylglutamic acid

(2S)-2-(carbamoylamino)pentanedioic acid

L-N-Carbamoylglutamic acid

Carbamino-L-glutamic acid

acido carglumico

Carbaglu

Definitions

A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.

ID

http://purl.obolibrary.org/obo/CHEBI_71028

charge

0

database_cross_reference

PMID:15055204

PMID:18234091

PMID:22858088

Drug_Central:3068

PMID:18516804

MetaCyc:N-CARBAMYL-L-GLUTAMATE

DrugBank:DB06775

PMID:21225012

PMID:21207059

PMID:18604903

Reaxys:1727929

PMID:21941437

CAS:1188-38-1

HMDB:HMDB0015673

Wikipedia:Carglumic_acid

PMID:20410539

PMID:17421020

KEGG:D07130

KEGG:C05829

PMID:21403788

formula

C6H10N2O5

has role

http://purl.obolibrary.org/obo/CHEBI_71033

http://purl.obolibrary.org/obo/CHEBI_71031

has_exact_synonym

N-carbamoyl-L-glutamic acid

has_obo_namespace

chebi_ontology

has_related_synonym

acidum carglumicum

carglumic acid

acide carglumique

Ureidoglutaric acid

Carbamylglutamic acid

(2S)-2-(carbamoylamino)pentanedioic acid

L-N-Carbamoylglutamic acid

Carbamino-L-glutamic acid

acido carglumico

Carbaglu

has_RxCUI

401713

id

CHEBI:71028

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1

inchikey

LCQLHJZYVOQKHU-VKHMYHEASA-N

label

carglumic acid

Carglumic acid

mass

190.15400

monoisotopicmass

190.05897

notation

CHEBI:71028

prefixIRI

CHEBI:71028

prefLabel

Carglumic acid

smiles

NC(=O)N[C@@H](CCC(O)=O)C(O)=O

textual definition

A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.

subClassOf

http://purl.obolibrary.org/obo/CHEBI_21650

http://purl.obolibrary.org/obo/CHEBI_47857

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