Preferred Name | Glipizide | |
Synonyms |
Glydiazinamide 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea Aldiab CP 28,720 CP 28720 CP-28,720 Digrin Dipazide Glibenese Glibetin Glican Glidiab Glipid Gluco-Rite Glucolip Glucotrol Glucozide Glupitel Glupizide Glyde K 4024 Melizide Mindiab Minidab Minidiab Minodiab Napizide Ozidia Sucrazide glipizida glipizide glipizidum N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide |
|
Definitions |
An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_5384 |
|
alternative term |
Glydiazinamide 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea Aldiab CP 28,720 CP 28720 CP-28,720 Digrin Dipazide Glibenese Glibetin Glican Glidiab Glipid Gluco-Rite Glucolip Glucotrol Glucozide Glupitel Glupizide Glyde K 4024 Melizide Mindiab Minidab Minidiab Minodiab Napizide Ozidia Sucrazide glipizida glipizide glipizidum N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide |
|
bearer_of |
http://purl.obolibrary.org/obo/CHEBI_35526 |
|
charge |
0 |
|
database_cross_reference |
PMID:7660535 Wikipedia:Glipizide Patent:US3669966 PMID:24418334 Reaxys:903495 Patent:DE2012138 CAS:29094-61-9 HMDB:HMDB0015200 PMID:3923454 PMID:11147395 DrugBank:DB01067 PMID:20797618 PMID:2665487 PMID:3143256 PMID:389600 LINCS:LSM-2251 Drug_Central:1301 PMID:23230096 PMID:24444583 KEGG:D00335 |
|
formula |
C21H27N5O4S |
|
has role |
http://purl.obolibrary.org/obo/CHEBI_35526 |
|
has_exact_synonym |
N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
Glydiazinamide 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea Aldiab CP 28,720 CP 28720 CP-28,720 Digrin Dipazide Glibenese Glibetin Glican Glidiab Glipid Gluco-Rite Glucolip Glucotrol Glucozide Glupitel Glupizide Glyde K 4024 Melizide Mindiab Minidab Minidiab Minodiab Napizide Ozidia Sucrazide glipizida glipizide glipizidum |
|
has_RxCUI |
4821 |
|
id |
CHEBI:5384 |
|
in_subset | ||
inchi |
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28) |
|
inchikey |
ZJJXGWJIGJFDTL-UHFFFAOYSA-N |
|
label |
glipizide Glipizide |
|
mass |
445.53500 |
|
monoisotopicmass |
445.17838 |
|
notation |
CHEBI:5384 |
|
prefixIRI |
CHEBI:5384 |
|
prefLabel |
Glipizide |
|
smiles |
Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 |
|
textual definition |
An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. |
|
subClassOf |
http://purl.obolibrary.org/obo/CHEBI_62733 http://purl.obolibrary.org/obo/CHEBI_38314 |