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Physician Data Query
| Preferred Name | linagliptin | |
| Synonyms |
BI 1356 BS Tradjenta 1H-purine-2,6-dione, 8-((3R)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)- (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione BI-1356 8-((3R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione |
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| Definitions |
A potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. The inhibition of DPP-4 by linagliptin appears to be longer lasting than that by some other DPP-4 inhibitors tested. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C83887" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C83887" NCI Thesaurus) |
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| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000793591 |
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| altLabel |
BI 1356 BS Tradjenta 1H-purine-2,6-dione, 8-((3R)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)- (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione BI-1356 8-((3R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione
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| CAS Registry |
668270-12-0
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|
| cui |
C3153996 C2352547 C2746078
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| DATE FIRST PUBLISHED |
2018-06-11
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| Date last modified |
2018-06-11
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|
| definition |
A potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. The inhibition of DPP-4 by linagliptin appears to be longer lasting than that by some other DPP-4 inhibitors tested. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C83887" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C83887" NCI Thesaurus)
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| LT |
TRD
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| NCI ID |
C83887
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|
| notation |
CDR0000793591
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| ORIG STY |
Drug/agent
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| prefLabel |
linagliptin
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| tui |
T109 T121
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